Rakhi Gibbons
Asst. Director, Life Sciences (520) 626-6695New technologies delivered to your inbox Subscribe
Devices, System and Method for Evaluation of Body and Appendage Volume/Girth
ua18-010 – Invention: This invention quantitatively monitors swelling to provide appropriate treatment. Background: A variety of sources pose serious risks to people, including venomous animals, infectious microbes, and environmental toxins. Envenomation involves the process of venom entering into the body, which causes edema. Fluid builds up and the local tissue swells. This follows... Read More
Proteins From Asthma-Protective Amish Farm Dust
ua18-035 – Title: Proteins from Asthma-Protective Amish Farm Dust Invention: This technology involves 8 proteins that have been identified from fractions of Amish farm dust, which have been shown to protect against asthma in mice models. These 8 proteins consist mainly of environmental allergens that can induce an immune response and have the potential to be utilized for allergen immunotherapy to... Read More
Method and Apparatus for Processing Electrochromic Materials and Devices
ua17-090 – Title: Method and Apparatus for Processing Electrochromic Materials and Devices Invention: This technology is a new process for developing full color electrochromic displays for various industries including a contact printing process for patterning of electrochromic materials on rigid, flexible, and curved areas. In addition, it includes a means for assembly and usage of bench-top... Read More
Compositions and Treatments for Haemophilus Influenzae
ua18-091 – Title: Compositions and Treatments for Haemophilus Influenzae Invention: This invention involves the generation, manipulation and administration of a non-toxic, broadly cross-reactive immunoprotective nontypeable H. influenzae vaccine. Background: H. Influenzae (Hi) is a Gram-negative anaerobic pathogenic bacterium responsible for causing otitis media (inner ear inflammation) in... Read More
A Method to Treat Post-Operative Atrial Fibrillation in Patients Undergoing Cardiac Bypass Surgery
ua17-252 – A Method to treat post-operative atrial fibrillation in patients undergoing cardiac bypass surgery
Concurrent Injection of Biomaterial Improves Efficacy of TMR Therapy
ua18-086 – Title: Concurrent Injection of Biomaterial Improves Efficacy of TMR Therapy Invention: This invention uses an extracellular matrix derived from the amniotic membrane that is injected with stem cells to increase vascularization of heart scar tissue after surgery with transmyocardial revascularization therapy. Background: Advanced heart failure continues to be a prevalent cause of... Read More
“Digital Reflexes”: Quantitation and Signatures of Superficial Reflexes via Stretchable Electronic Wearable Sensors
ua18-128 – Title: “Digital Reflexes”: Quantification and Signatures of Superficial Reflexes via Stretchable Electronic Wearable Sensors Invention: This invention provides a method of deep tendon reflex assessment via stretchable electronic sensors containing tri-axial accelerometers and EMG signal detection, which allows for quantitation of motion and EMG “signatures” of a specified reflex. ... Read More
PAR 2 Inhibitors
ua18-135 – Title: PAR 2 Inhibitors Invention: This invention describes new inhibitors of the protease activated receptor 2 (PAR2), a G protein coupled receptor (GPCR) involved in inflammatory related diseases, for the treatment of asthma and a wide range of other diseases. Background: It is estimated that by 2025 400 million people will be suffering from asthma. While the prevalence of asthma... Read More
Biomarker Signatures of Platelet Activation
ua18-230 – Title: Biomarker Signatures of Platelet Activation Invention: This invention is a mechanical biomarker signature of shear effects on cells for the purpose of detecting thrombosis early so it can be treated or intercepted prior to a thrombotic event. Background: Thrombosis is a pathophysiological event that can trigger conditions like stroke or heart attack. The efficacy of many... Read More
Method for Identifying Novel Peptide and Peptidomimetic Agonists and Antagonists to Protease-Activated Receptors
ua12-040 – No summary available
Enteral Electrical Constructs
ua17-051 – Title: Enteral Electrical Constructs Invention: This invention is a diagnostic and therapeutic system that is composed of ingestible, edible, and nutritive electric/electronic constructs in order to measure various aspects of the entire digestive system. Background: Electronic systems are vital in medical diagnostics and therapeutics, but current electronic systems are based largely... Read More
tPTX Device for Modified Veress Needle Assembly
ua16-121 – Title: Veress Needle Interface for Tension Pneumothorax Decompression Invention: Inventors at the University of Arizona have designed an interface for the modified Veress needle (mVN) to address the shortcomings of older devices used to treat tension pneumothorax such as traditional needle thoracostomy (NT). This interface serves as an attachment that adds additional functionality to the... Read More
Pharmacogenomics of Intergenic SNPs and in Silico Modeling for Precision Therapy
ua16-224 – Title: Pharmacogenics of Intergenic SNPs and in Silico Modeling for Precision Therapy Invention: A method for analyzing a single patient’s DNA and modeling how mutations and variations in intra-cell genomics will be expressed in the body. The information may be used to develop highly personalized therapies without the need for huge experimental data sets. Background: Personalized... Read More
Method, Device and System for Appendage Protection Therapy (Smart Offloading Boot)
ua15-080 – Smart Insole Introduction: Diabetic foot ulcers require a lot of monitoring for the wound healing process. Patients are asked to perform self-evaluations in between physician visits in order to keep an eye on high risk factors during the healing process. If high risk factors are found patients must then get into the doctor for treatment. This process leaves a lot of room for complications... Read More
Health Buddy
ua15-187 – Title: Mobile Platform for Tracking and Understanding Health Invention: Inventors at the University of Arizona have developed a mobile platform designed to help patients improve the understanding of their health data, as well as communicate more effectively with medical professionals. Envisioned as an application that improves the efficiency of the relationship between patients and... Read More
Systems, Methods, Devices and Materiel for Definition, Monitoring and Modulation of Organism Strength
ua16-024 – Title: Health Behavior Change Training Program (Reach) Invention: An in-person workshop and website that provides information and training for “helpers” and/or complementary and alternative medicine (CAM) practitioners aid individuals in changing harmful health behaviors, including tobacco cessation. The training, associated with CAM, focuses on “helping conversations” that avoid... Read More
Systems, Methods, Devices and Materiel for Definition, Monitoring and Modulation of Organism Flexibility
ua16-025 – Title: Health Behavior Change Training Program (Reach) Invention: An in-person workshop and website that provides information and training for “helpers” and/or complementary and alternative medicine (CAM) practitioners aid individuals in changing harmful health behaviors, including tobacco cessation. The training, associated with CAM, focuses on “helping conversations” that avoid... Read More
Methods, Systems and Devices for Codification, Analysis and Monitoring of Motion or Motion Description and Analysis System
ua16-241 – Title: Methods, Systems and Devices for Codification, Analysis and Monitoring and Motion or Motion Description and Analysis System Invention: The technology consists of wearable, thin, stretchable electronic systems. These wearable trackers have accelerometers and gyroscopes to capture coordinates, dimension, velocity, and acceleration data. Background: In order for a motion tracking... Read More
Point of Care Microfluidic Aggrogometer
ua17-170 – Title: Point of Care Microfluidic Aggrogometer Invention: The invention is a device to assess platelet aggregation for diagnosis of thrombotic diseases and continual monitoring with anti-platelet therapy. Background: Heart disease is the leading cause of death in the United States and, with over 50% of those deaths due to clot formation from myocardial ischemia and infarction.... Read More
Compositions and Methods for Detecting Complicated Sarcoidosis
ua17-208 – Title: Compositions and Methods for Detecting Complicated Sarcoidosis Invention: The invention is a novel biomarker capable of identifying complicated sarcoidosis, as well as patients at risk for increased morbidity due to sarcoidosis. Background: Sarcoidosis is an inflammatory disease involving abnormal collections of cells that form lumps and typically begins in the lungs. Genetic... Read More
Targeting Extracellular NAMPT and TLR4 as a Therapy for Pulmonary Arterial Hypertension
ua17-159 – Title: Targeting Extracellular NAMPT and TLR4 as a Therapy for Pulmonary Arterial Hypertension Invention: The invention is the targeting of nicotinamide phosphoribosyltransferase (NAMPT) for the treatment of pulmonary arterial hypertension. Background: Pulmonary arterial hypertension is a progressive disease that leads to increased resistance and eventual right ventricular failure and... Read More
Interface
ua16-061 – Title: Sensor Interface for Preventing Tissue Damage Invention: Inventors at the University of Arizona have developed a sensor interface designed to detect and prevent tissue damage. The device is attached to the subject’s skin, senses and identifies regions within the skin-contact surface at risk for damage from these stressors, and then makes adjustments to those regions in order to... Read More
Systems and Signatures for Cardiopulmonary Resuscitation
ua17-136 – Title: Systems and Signatures for Cardiopulmonary Resuscitation Invention: The invention is a system and method to quantify optimal CPR through the Bio-Stamp. This system will monitor and provide feedback to the CPR provider if CPR is being performed correctly, allowing the CPR provider to make corrections and standardizing the way to individuals are trained in CPR. Background:... Read More
Protease-Activated Receptor Type 2 Modulators and Inhibitors
ua14-181 – Invention: UA14-181 is a novel and highly potent PAR modulator. Because PAR activation plays a pivotal role in a variety of inflammatory diseases, high affinity and potent ligands of the PAR receptor like those found in UA14-181 represent a novel approach to the prevention and treatment of inflammatory diseases. Background: PAR is a well-known cell surface receptor that is involved in the... Read More
PAR3 Inhibitors as Therapeutic for Pain
ua16-176 – Title: PAR3 Inhibitors as Therapeutic for Pain Invention: The technology identifies protease activated receptor-3 (PAR3) and PAR3 inhibitors as a novel target for the treatment of pain. Background: Pain is one of the most common reasons in which individuals seek medical attention. Globally, pain affects at least 1.5 billion people, with the incidence rate increasing complementary to... Read More
Sweat Biomarkers as an Indication of Physiological Conditions
ua14-146 – Title: Sweat Biomarkers as an Indication of Physiological and Psychological Conditions Invention: Inventors at the University of Arizona have devised a means by which cortisol isomer ratios in human sweat can be measured and used to evaluate the physiological or psychological state of the patient. Certain cortisol isomer ratios are associated with particular conditions or disorders (high... Read More
Prostate Cancer Patient Blood Sample Collection and PSA Survey
ua10-061 – Blood samples collected from participants in the NIH-funded Watchful Waiting Study, a study of selenium supplementation in men with prostate cancer. Samples were processed to prepare plasma and tested for Prostate Specific Antigen (PSA) level. Samples are available for licensing.
Smart Textile to Predict Diabetic Foot Ulcer
ua15-161 – Title: Smart Textile to Predict Diabetic Foot Ulcer Invention: The invention is a movable, washable smart textile that can measure abnormalities in pressure and temperature when a patient applies pressure while walking on it. The textile can analyze the data and send alerts to the patient when abnormalities suggest the presence of diabetic foot ulcers (DFU) and/or the likelihood of falls... Read More
Method for Determining Cell Stiffness
ua15-179 – Title: Method for Determining Cell Stiffness Invention: The present invention is a minimal-contact method used to trap and measure the stiffness of platelets in relation to the whole cell. Background: Platelets, essential for hemostasis, are easily activated via biochemical and mechanical stimuli. In addition, cell stiffness is a vital parameter modulating the mechano-transduction of... Read More
Treatment for Type II Diabetes
ua16-043 – Title: Biomarkers of metformin efficacy and methods related to Type II diabetes Invention: The present invention provides methods, compositions, and related uses for the interaction between metformin and methylglyoxal. In addition, this invention provides methods for detecting the efficacy of metformin therapy while exploring the metformin-MG reaction, unequivocally determining the... Read More
Virtual Reality Systems and Methods for Improving Clinical Outcomes
ua16-018 – Title: Virtual Reality Treatment System Invention: The invention provides a virtual reality (VR) experience, including VR goggles and haptic feedback devices, for patients to explain the benefits of a medical treatment or the consequences of non-compliance. The immersive experience seeks to have a greater impact on a patient’s behavior versus a discussion with a healthcare provider alone.... Read More
Smart Insole
ua15-079 – Technology ID: UA15-079 Technology Background: Diabetic foot ulcers impact nearly 1 in 4 patients with diabetes. Over 50% of those who do develop foot ulcers requiring hospitalization at some point in their lives. Once infection sets in, amputation may be the only option for the patient’s survival. Approximately 1 in 5 foot ulcers will require amputation, and over 80% of lower limb,... Read More
Novel microRNA Gene Expression Profiling for Sarcoidosis Diagnosis
ua15-193 – Title: Novel microRNA gene expression profiling for sarcoidosis diagnosis Invention: The invention is a microRNA (miRNA) regulated gene signature that can detect sarcoidosis in patients. The invention consists of 46 miRNAs and 1,559 genes that were differentially expressed with sarcoidosis severity. In addition, 17 genes were identified to form a diagnostic scale. A high score on the... Read More
Reactive Oxygen Species Gene Signature Predicts Survival in Sepsis
ua16-068 – Title: Reactive oxygen species gene signature predicts survival in sepsis Invention: The technology is a 21-gene reactive oxygen species (ROS)-associated molecular signature that predicts survival in septic patients. Background: Sepsis syndrome’s mortality rate is 26% to 82% depending on whether septic shock occurs. Currently there are no reliable diagnostic biomarkers available to... Read More
Biostable Segmented Elastomers and Engineering Thermoplastics
ua14-016 – A continuing need exists for biostable, tough elastomers, particularly for use in long-term, dynamic medical implants (including, but not limited to: cardiac pacing lead insulation, cardiac assist device bladders, chronic indwelling catheters, and other medical implants subject to biodegradation). Existing elastomers used in these applications (e.g. polydimethylsiloxanes and segmented... Read More
An in Vitro Cellular Bioassay for Assessment and Investigation of Neurotoxicity
ua10-103 – Title: In vitro neurotoxicity screening Invention: The present invention provides high speed, low cost, and highly accurate neurotoxicity and developmental neurotoxicity screening methods for a wide variety of compounds. Background: Neurotoxicity tests are designed to generate definitive data concerning the adverse effects of a neurotoxic substance on human or animal health or the... Read More
Health Information (Data) Medical Collection, Processing and Feedback Continuum Systems and Methods
ua16-015 – Title: Health Information Collection System Invention: The Health Information Continuum is a system for collecting and processing HI data for individual patients across multiple health care provider interactions. The system expands the amount and type of data collected by current HI systems to create a more complete representation of a patient’s health. Furthermore, the broad scope of... Read More
Systems and Methods of Analyzing Healthcare Data
ua16-016 – Title: System for Analyzing Healthcare Data Invention: The invention includes systems and methods for collecting and analyzing healthcare information to provide complete, automated health records for patients. The analytic system accepts a broad range of raw data which is translated into concepts using knowledge-bases and then applied to electronic health records (EHR). Background:... Read More
Patient Coordination System and Method
ua16-017 – Title: Hospital Patient Monitoring and Tracking System Invention: The invention tracks and monitors patients in a hospital or other healthcare facilities to manage scheduling of tests and procedures based on health priority and cost. The system organizes an optimum schedule to reduce the duration of hospital stays for all patients and ensures that each patient promptly receives the... Read More
Dyzo- Piezo Electric System for Measuring Tissue Properties
ua15-157 – Title: Skin Monitoring system Invention: This device is a flexible sensor capable of conforming to the skin of a patient to record data relevant to overall skin health. Background: The device tracks the variable elastic modulus between healthy and unhealthy skin. This can determine efficacy of beauty products that claim to deliver healthier skin to users or even detect malignant... Read More
Polymeric Heart Valve
ua14-011 – Background: Currently, in artificial heart valves, chemically fixed animal tissue is used. While such tissue has numerous advantages in durability, it carries with it the costs of processing and implanting xenographs. Additionally, one problem with these grafts is that their durability highly depends on the age and condition of the patient. Thus, there exists a need for a highly... Read More
Aerostasis in Pulmonary Surgery
ua13-116 – Introduction: Serosal tissue damaged during surgery needs to heal, but patients are often at risk of infection during recovery. This can lead to higher morbidity rates, longer hospital stays, or death. Likewise, lung tissue is at risk of leaking after surgery, which causes the same problems. Doctors currently use human fibrin gel to address these issues, but its effectiveness is somewhat... Read More
HeCOS
ua14-018 – Background: Current home-based RAD devices work by administering air or a mixture of air and oxygen under high pressure. These Conventional positive-airway pressure therapies administered in the home setting are poorly tolerated in patients requiring respiratory assist devices. The reasons for such poor tolerance are the high airway pressure administration which, In turn, causes noxious... Read More
Piezo Electric Energy Harvesting System
ua14-076 – Background: Pacemakers and other similar implantable medical devices suffer from the shortcoming of limited battery life. When the useful life of the batteries powering these devices has expired, surgical procedures are usually necessary to replace them. Like all surgeries, these procedures involve undesirable risk to the patient, patient discomfort, and utilization of healthcare resources... Read More
Motion Correction for PET and SPECT
ua14-117 – Background Motion artifacts are disruption in medical images caused by motion of the object being imaged. The elimination of motion artifacts is important when using multi-modality imaging systems; for example, Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT), and MRI/SPECT (Magnetic Resonance Imaging). During operation, these systems may exhibit... Read More
Diagnostic for Gastrointestinal Dysfunction
ua14-143 – Children undergoing cardiopulmonary bypass for repair or palliation of congestive heart disease are at risk for intestinal injury and often present with altered intestinal barrier function. Monitoring markers of intestinal injury may lead to innovative pre- and post-operative gut-protective measures during various illness states. UA14-143 is a novel bio-marker diagnostic for use in... Read More
Monoclonal Anticytokeratin Antibody (Ka2)
ua04-016 – Title: Monoclonal Antibody for the Diagnosis of Prostate Cancer Background: Prostate cancer is the most common type of cancer, displacing lung cancer as the number one visceral malignancy in males in the United States. Despite its growing prevalence relatively little is known about its malignancy. Currently, there is a lack of animal models to further research and supplies of cell... Read More
Radial Fast Spin-Echo (Fse) MRI Pulse Sequence
ua09-028 – Introduction: MRIs are very useful tools for imaging inside the human body without having to do invasive surgery. Two of the drawbacks to this technology currently are 1) low resolution of imaging and 2) length of time required to image. Invention: Radial imaging is a way of taking MRI data radially (from the center, out). This invention is a software method that combines radial... Read More
Mixture of Estrogens Selective for Estrogen Receptor Beta for Treatment of Neurological or Psychiatric Disorders
ua14-052 – This technology provides a mixture of estrogens that are selective for ER-β activation, offering a novel treatment for neurological and psychological disorders. Mental disorders are the number one contributor to non-communicable diseases worldwide. Mental disorders such as schizophrenia, mood disorders, substance abuse and dementia contribute more to global disease burden than cancer or... Read More
P-Mod: An Algorithm and System to Match Mass Spectral Data of Variant or Modified Peptide Sequences
ua02-002 – Title: P-MOD: An Algorithm and System to Match Spectral Data of Variant or Modified Peptide Sequences Background: Tandem mass spectrometry (MS-MS) is a widely used research tool for the characterization of proteins. This method provides spectral data about the sequence of peptides allowing researchers to identify the proteins from which these peptides are derived. The data... Read More