Stabilized Black Lipid Membranes Prepared via Polymer Scaffolding

Technology #ua14-172

Questions about this technology? Ask a Technology Manager

Download Printable PDF

Steven scott Saavedra
Professor, Chemistry & Biochemistry
Leonard Bright
Graduate Assistant, Chemistry & Biochemistry
Craig Aspinwall
Professor, Chemistry
Managed By
Laura Silva


This invention presents a new approach for stabilizing BLMs relying on inexpensive commercially available materials. Here, a method is employed that chemically modifies the lipid membrane to dramatically improve BLM stability.



Black lipid membranes (BLMs), are synthetic membranes used to measure ion channel activity. Suspended Lipid Membranes, BLMs, provide a key technological platform for the incorporation of ion channels and other biological nanopores. These nanopore membranes play a key role in DNA sequencing, biochemical sensing and have potential applications in medical diagnostics, environmental and biological sensing and other arenas. Limitations of BLMs are the poor chemical, mechanical, temporal and environmental stability, which restricts utilization to specialized operations.



  • DNA Sequencing
  • Biochemical Sensing
  • Medical Diagnostics
  • Environmental Sensing
  • Biological Sensing
  • Nanopore Sequencing
  • Nanopore Sensing
  • Nanopore Diagnostics


Using this approach BLMs are formed that support ion channel activity and are stable in excess of day one.



Craig Aspinwall

Associate Professor Chemistry and Biochemistry, Biomedical Engineering

University of Arizona

Phone: 520-621-6338



Leonard Bright

Graduate Student Chemistry and Biochemistry

University of Arizona

Phone: 520-626-1335



Steven Saavedra

Professor Chemistry

University of Arizona

Phone: 520-621-9761



Licensing Manager:

Laura Silva

(520) 626-1557 


Stage of Development

Proof of Concept: Partially Demonstrated

UA ID: UA14-172