Fluorogenic Diazonium-Derived FluorophoresTechnology #ua16-038
Questions about this technology? Ask a Technology Manager
- Mehrdad Shadmehr Graduate Assistant, CBC
- Bereketab Mehari Graduate assistant, CBC
- John Jewett Assistant Professor, Chemistry & Biochemistry
- Managed By
- Laura Silva
Title: Fluorogenic Diazonium-Derived Fluorophores
Invention: The technology describes various diazonium salts that can react to produce a fluorescent azobenzene compound.
Background: Current iterations of fluorescent diazonium salts utilize metal catalysts to produce a reaction. However, these metal catalysts can have harmful effects in a medical setting. This invention consists of a bioorthogonal approach performed under physiological conditions to produce fluorescent compounds that can be bound to specifically targeted proteins.
- Detection and diagnostics
- Medical imaging
- Ideal for medical settings
- Reduces the likelihood of false positives
- Able to bind to various proteins,
- Targets and detects a wide variety of compounds