Solvent-Free and Additive-Free Nitration of ArenesTechnology #ua16-131
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Title: A simple synthetic process for the nitration of aromatic compounds
Invention: The University of Arizona presents a novel, one-step, catalyst-free, and solvent-free synthetic process for the nitration of aromatic compounds. This method has been used to prepare 2,4-dinitroanisole, an alternative to trinitrotoluene (TNT), as an ingredient in melt-cast explosive formulations; and dinitrophenyl ethers. This synthetic process can be utilized to produce a variety of nitroaromatic compounds in a fast, straightforward, and more economical fashion than traditional chemical methods.
Background: Traditional synthetic nitration methods often employ catalysts, solvents, or other additives that are harmful to the environment and/or expensive. This synthetic process overcomes these issues by allowing the nitration of various aromatic compounds in a catalyst-free and solvent-free fashion.
- Explosives for mining, construction or military purposes
- Metabolic disease therapeutics
- Fermentation process aid
- Requires only one step
- Maintains a highly selective process
- Does not require the use of a solvent, therefore reducing cost
- Does not require the use of expensive, harsh, or toxic catalysts
- Exhibits increased efficiency over other reported methodologies
- Retains a broad reaction scope