A Method for Uncovering Cross-Linked Peptides by Mass SpectrometryTechnology #ua17-008
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Title: Unique Process to Identify Drug Binding to Targets
Invention: The invention is a unique fragmentation pattern to identify cross-linked peptides in a mass spectrometer.
Background: Progress in drug discovery is generally hampered by a lack of understanding of how the medication works and how the drugs binds to its target. This technology provides a way to identify cross-linked peptides via a unique fragmentation pattern that aids in identifying the drug-binding region.
- Drug discovery
- Lab research tool
- Allows for identification in complex mixtures (whole cells or tissues)
- Provides an alternative unique fragmentation pattern to further research in medications' mechanism of action