A Novel Approach to Single-Cell Amperometry Using an All-Polymer Microfluidic ChipTechnology #ua17-034
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- Michael Heien Associate Professor, Chemistry & Biochemistry
- Richard Vreeland Graduate Assistant, Chemistry & Biochemistry
- Adam Meier Graduate student, CBC
- Rafael Taboryski Associate Professor
- Marco Matteucci post doc
- Managed By
- Paul Eynott Sr. Licensing Manager (520) 621-2878
Title: A Novel Approach to Single Cell Amperometry Using an All-Polymer Microfluidic Chip
Invention: The invention describes a novel manufacturing method for a chip that can perform amperometry on a cellular level. This chip can capture single cells and measure electrochemical output. The current design is calibrated towards dopamine release.
Background: Single cell amperometry is a powerful technique that can measure the neurochemical release from a cell. Existing techniques rely on manual fabrication and positioning of electrodes to achieve usable results. The invention described here would eliminate the need for manual fabrication.
- A cell analysis apparatus
- A diagnostic tool/service to sample a series of cells to identify what electrochemical anomalies are present
- Does not need to be manually fabricated and can be automated, allowing the invention to be more cost effective in the long run, which makes more efficient and controlled measurements
- Possesses the potential to create a chip that can be used to study cells in bulk for accurate electrochemical measurements