Enhanced Microfluidics PDMS Pneumatic Valve

Technology #ua17-038

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Craig Aspinwall
Professor, Chemistry
Christopher Baker
Postdoctoral, CBC
Xuemin Wang
Graduate Student, CBC
Managed By
Laura Silva

Title: Enhanced Microfluidics PDMS Pneumatic Valve


Invention: The invention significantly improves the resistance of pneumatic valves in microfluidic arrays to >500 GΩ (an order of magnitude improvement) with fast opening and reasonable closing times as well as good stability. The result is greatly improved signal-to-noise ratio (SNR) resulting in higher analytical throughput at lower cost.


Background: Microfluidic arrays are used for electrophysiological recordings in a variety of research and diagnostic analyses, particularly drug screening. Improvements in microfluidic array operations lead to increased speed and lower cost in testing and R&D applications.  


  • Lab-on-a-chip
  • Drug development, cellular, DNA and proteomic research
  • Tunable microlens arrays and optofluidic microscopes
  • Fuel cells



  • Improved signal-to-noise ratio (SNR)
  • Higher throughput analytics leading to lower costs


Licensing Manager:

Laura Silva


(520) 626-1557