Detection of Folding State of a Macromolecules by Chemical Conjugation

Technology #ua17-041

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Researchers
Mahta Moinpour
Graduate Student, Chemstry & Biochemistry
Jacob Schwartz
Assistant Professor, Chemistry & Biochemistry
Managed By
Laura Silva

Methods and systems for detecting, comparing, or evaluating proteins in an folded conformation, a particular bound state, or an aggregate state, and methods and systems for comparing amounts of labeling of a protein in a natural or control conformation and a denatured conformation. The methods of the present invention may be used for a variety of applications including but not limited to evaluation of protein aggregates levels related to a particular disease (e.g., aggregate-associated disease, etc.), possibly for diagnostic purposes.

 

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