Apparatus for Reconfiguration of Components in a Micro-Physiological System

Technology #ua17-076

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Matthew Barrett
Research Specialist, Sr., ANBM
Frederic Zenhausern
Director, COM-PHX Applied NanoBioscience & Medicine
Marc Mac Giolla Eain
Visiting postdoc
Paul Wilmes
Managed By
Rakhi Gibbons
Asst. Director, Life Sciences (520) 626-6695

Title: Apparatus for Reconfiguration of Components in a Micro-Physiological System


Invention: The invention is a novel apparatus utilizing modular assembly for the development of co-culture, monitoring, and study of functional interactions between different types of biological material under various environmental conditions. The buckle clamp stage-like apparatus mimics a microfluidic based system.


Background: 3D in vitro models are important for studying the functional interactions of the human microbial ecosystems on human tissue. This requires a device that has various components and flexibility to accommodate specific operating conditions and experimentation. In vitro microphysiological systems generally require multiple chambers of cellular culture and a nutrients perfusion chamber. This technology aims to provide alternative to the current microphysiological systems.



  • Laboratories
  • Biotechnology companies
  • Drug research



  • Quick disassembly time
  • Requires less time to train
  • Reduces risk for contamination when accessing internal cellular components via modular assembly
  • Improves accuracy and quality of data collected


Licensing Manager:

Rakhi Gibbons

(520) 626-6695