Dihydrotetrazine Antioxidants and Free Radical Reaction Inhibitors

Technology #ua17-110

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Wenmo Sun
Graduate assistant, 26 Chemistry & Biochemistry
Robb Bagge
Graduate assistant, CBC
Douglas Loy
Professor, 20 Materials Science & Engineering
Managed By
Robert Sleeper
Licensing Manager (520) 626-4604

Title: Dihydrotetrazine Antioxidants and Free Radical Reaction Inhibitors


Invention: The invention is the use of dihydrotetrazines as antioxidants to eliminate free radicals. Dihydrotetrazines were found to be superior to dihydropyridazines or hindered phenols in inhibiting free radical polymerization.


Background: Dihydrotetrazines donate up to two hydrogen atoms to terminate radical chain or oxidation ractions. These compounds can be prepared in the synthesis of tetrazines or by hydrogenation or reduction reactions.



  • Plastics/rubber
  • Food
  • Cosmetics
  • Pharmaceuticals
  • Fuel



  • Can serve as an alternative antioxidant agent
  • Increases efficacy


Licensing Manager:

Paul Eynott


(520) 471-2687