Coded-Aperture System for Planar Imaging of Volumetric Sources

Technology #ua98-033

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Categories
Researchers
Harrison Barrett
Professor, Optical Sciences
Eric Clarkson
Professor, Medical Imaging
Donald Wilson
Research Associate Professor, Radiology
Managed By
Amy Phillips
Sr. Licensing Manager (520) 621-9579

Title:Coded-Aperture System for Planar Imaging of Volumetric Sources

Introduction: Nuclear medical imaging encompasses scintigraphy (using internal radionuclides and gamma cameras to produce 2D images) and Single Photon Emission Tomography, or SPECT (producing 3D images through use of similar techniques combined with tomographic 3D reconstruction methods).  2D imaging methods utilizing collimators produce relatively low resolution images, and resolution degrades with greater depth of the imaged object. Existing methods that utilize coded apertures and semiconductor detectors for 2D nuclear imaging suffer from increased mechanical complexity while offering only marginal improvements in resolution degradation with depth in 3D objects. 

Invention: UA098-033 is a method for obtaining parallel projections (i.e. 2D planar images) of a 3D object without the use of a parallel bore collimator while offering improved resolution and decreased resolution degradation with increasing object depth. The method involves measuring the photon flux of a gamma photon emitting source from within the subject’s body in a novel fashion, and processing these measurements with computer software that utilizes a unique mathematical process. 

Advantages:

Enhanced resolution

Decreased resolution degradation with increasing object depth   

Applications: 

Planar, 2D nuclear medical imaging

3D nuclear medical imaging technologies like Single Positron Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET)

Defense and homeland security

Gamma ray astronomy, particle physics

Early pharmaceutical development, and molecular biology.   

Lead Inventor: Harrison Barrett

Stage of development: Demonstrated proof of concept

 

IP Status: Issued patent  

Contact:  Amy Phillips; amyp@tla.arizona.edu

Refer to case number UA98-033