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Novel Inhibitors of GAB1
ua15-036 – Technology Background: Outside of biological treatments, there are other ways to treat cancer. These include: surgery, chemotherapy, and radiation therapy. Surgery is usually only used in cancer that is isolated in one place and not metastasized cancer (Kubota 227). Chemotherapy has ill side-effects due to it targeting many fast growing cells (Chemotherapy Drugs and Side Effects). Radiation... Read More
Metal Free Scalable Synthesis of Fluorinated Indole and Benzofuran Structures
ua15-027 – Technology Background: There are few alternative existing methods to treat arrhythmia. Originally, there were a slew of powerful anti arrhythmic drugs on the market which had the potential to treat the cardiovascular condition. However, the majority of these drugs were revealed to actually increase mortality rates rather than decrease them (Matyus, et. al 61). This left only two major... Read More
Drugs for L-Dopa-Induced Dyskinesia
ua15-023 – Background: Parkinson’s disease is the second most common neurodegenerative disorder, with an incidence of about 2% in the population over 60 years. Parkinson’s is known to cause the loss of motor skills, such as bradykinesia, postural instability, resting tremor, and rigidity. The precursor of dopamine, levodopa, is highly effective in relieving Parkinson’s motor symptoms during the... Read More
Cooperative Modulation Classification in Cognitive Radio Networks
ua14-110 – This invention presents a novel algorithm and system for distributed modulation classification of multiple synchronous transmitters in a cooperative Cognitive Radio (CR) environment. This is done by using the joint probability of higher order statistics of the unknown signals. The invention proposes a distributed modulation classification algorithm consisting of two stages: calculation of... Read More
Real-Time Data Warehouse-Powered, Dynamically Generated Simulation System for Complex Processes
ua14-036 – Background Being able to generate simulation models is important to many industries because it helps assists companies in making strategic decisions. Most simulation models take time to build and are designed to answer very specific questions. This poses major challenges for industries that handle a lot of input data which needs to be processed quickly. In mining simulation models have... Read More
Sorbent for Removal of Perfluorinated Compounds From Water
ua13-072 – This technology consist of a sorbent that effectively removes perfluorinated compounds (PFCs) from water. The sorbent is a combination of two hydrophobic cationic polymers with structural modifications to enhance electrostatic and hydrophobic interactions with perfluorinated compounds. The polymers have the ability to remove PFCs in two ways: through ion exchange and hydrophobic... Read More
Assay Device With Tunable Array of Unique Steady-State Microfluidic Gradients
ua13-047 – An assay device based on the common T-shaped microfluidic geometry to produce an array of unique gradients. The Assay Device with Tunable Array of Unique Steady-State Microfluidic Gradients contains two reservoir channels, an intersection point, a source and sink channel, an array of microchannels and a shared exit port. Within the device there are two gradients developed: one that forms... Read More
Anisotropic Illumination Sensor
ua13-065 – This technology is a multi-detector solar irradiance sensor design which can measure both direct and diffuse light in a variety of conditions. Additionally, this device provides real time angular distribution measurements of the anisotropic diffuse illumination incident on solar electric panels. Photovoltaic systems are designed and tested based on standard conditions in which only... Read More
Computer-Aided Surgical Trainer (Cast)
ua12-113 – Minimally invasive surgery (MIS) is a modern surgical technique requiring small incisions or no incisions. This technology is a system for the assessment and training of minimally invasive surgical skills (MIS). The apparatus of the invention comprises a set of physical building units, sensors and actuators to embody a variety of training tasks. The sensors gather performance data on... Read More
A Photo-Bleach Test for Visually Impaired Patients
ua14-186 – Invention The Photostress Testing device detects visual changes in the retina before irreversible damage can occur. It works by temporarily blinding a small part of the retina called the fovea and tests the time it takes for full eyesight regeneration, a process known as photobleaching. Recovery times in healthy eyes are much shorter than in eyes with diseases such as macular... Read More
Repairable Data Blocks and Method of Data Block Reconstruction for Large Scale Cloud Storage Systems
ua14-112 – Invention: This invention is a new approach to reinforcing the storage system by storing the data with specifically placed redundancies that reduce the chance that all copies of the same data will be lost simultaneously. The invention also allows for possible reconstruction of lost data using remaining data. Background: Online cloud computing systems utilizing distributed data storage... Read More
Energy and Memory Efficient Analog to Digital Image Processing Method for Use in Data Intensive Systems
ua14-046 – Background: While most of the existing ideas in low power VLSI design are valid, there is also a need to focus on how we sample the external objects, extract the features, and process the data. Here, there is provided a completely different approach to low power design. Invention: The invention starts from the mixed signal data collection and integrates the sampling scheme with memory... Read More
Three-Dimensional Construct for Tissue Regeneration
ua14-023 – This technology is a three-dimensional cardiac construct that can be used to replace damaged tissue and promote tissue regeneration. The construct contains many variables of customization depending on the type of tissue that must be replaced. This technology will offer surgeons a way to replace necrotic tissue with a celluarized scaffold that can promote tissue regeneration. There are... Read More
Non-Damaging Megasonic Chip Cleaning Process
ua13-026 – Faculty at the University of Arizona propose a new low power process to eliminate particles on a patterned wafer without damaging its fragile features. The process greatly improves cleaning efficiency and is commercially viable for microchip manufacturers. The concept of cleaning patterned wafers using Megasonic bubbles is novel and provides a solution to develop and clean complex... Read More
Metallic Coating and Circuit Masking Using Nanoparticles
ua14-005 – This invention to cover metals, silica, or glass in a thin metal layer by disclosing the formation of a thin layer of metal from metal (i.e. copper, gold, silver, etc) nanoparticles by only the electrostatic interaction between the nanoparticles and a suitably prepared substrate surface. Electrostatic plating of metal nanoparticles allows for a method of coating both metal and... Read More
Coded-Aperture System for Planar Imaging of Volumetric Sources
ua98-033 – Title:Coded-Aperture System for Planar Imaging of Volumetric Sources Introduction: Nuclear medical imaging encompasses scintigraphy (using internal radionuclides and gamma cameras to produce 2D images) and Single Photon Emission Tomography, or SPECT (producing 3D images through use of similar techniques combined with tomographic 3D reconstruction methods). 2D imaging methods utilizing... Read More
Color Imaging Based on Computational Imaging and Narrow Band Absorption Color Filter Array
ua14-013 – Researchers at the University of Arizona have created a novel color filter array (CFA) that allows much more light to reach a detector than conventional CFAs. The novel arrangement of filters with respect to wavelength cutoffs allows for crisp digital imaging with half the ambient light level required by currently known CFAs. The advantage is especially beneficial for digital cameras,... Read More
Rapid and Reagentless Detection of Microbial Contamination Within Meat Utilizing Smartphone-Based Biosensor
ua14-066 – This technology detects and quantifies microbial contamination, without the use of any microbeads, antibodies, or laboratory instrumentation. This technology requires only a smartphone, the appropriate software, and an NIR LED. Development of rapid, non-destructive, and inexpensive sensing technologies for detection of microbial contamination of food products remain in high demand to... Read More
Method and Apparatus for Deep Ultraviolet Microscopy
ua07-048 – Method and Apparatus for Deep Ultraviolet Microscopy Optical microscopes have many applications in both industry and life sciences. In the semiconductor industry, visible light microscopes have been used for quality inspection because of their non-destructive advantage over electron microscopy, which can be damaging to the semiconductor wafers. However, as feature sizes in the semiconductor... Read More
Video Image Based Bed Load Analyzer
ua14-133 – This instrument enables the automation and accurate measurement of bed load transport rate using modern innovations in digital images, processing, and wireless technologies. Its novelty allows for analysis of sediment transport without collecting actual samples. Current methodology measures bed load sediment by grabbing samples of river bottoms physically, either by mechanical scoops... Read More
CHRE2D Software
ua14-132 – This technology is a computer software capable of simulating unsteady flood flow and river morphodynamic processes in waterways including natural rivers and manmade canals. The software consists of a suite of programs in Fortan and Matlab language. This software simulates surface flow routing using numerical solutions of shallow water equations and the kinematic or diffusion wave... Read More
"Rock Softening" Method and Apparatus for Efficient Drilling
ua14-114 – A method for improved material weakening including rocks, concrete, and other man-made materials. The method established uses an imbalance between the rate of energy input and the rate of energy dissipation in the material resulting in a more significantly more efficient material breakage process. This imbalance is established by reducing the rate of energy dissipation, employing a... Read More
A Fault Tolerant and Power Efficient Network-on-Chip Architecture Using Quad-Function Channel (Qfc) Buffers
ua14-104 – QORE is a fault tolerant Different Network on Chip (NoCs) that seeks to reduce power consumption and improve performance of NoCs while mitigating errors caused by faults. Through a new type of data buffer and connecting multiple processing cores QORE has the ability to reduce power and avoid faults. With electrical components shrinking in size, there has been remarkable growth in the... Read More
Vagus Relaxation App
ua15-018 – The University has a PCT patent application for this real time Heart Rate Variability monitoring technology. A working prototype smartphone app (currently for Android operating system) uses physiological data about the heart to relieve stress. This information is gathered from a Bluetooth-connected wearable biosensor that analyzes an individual’s stress level. When stress levels are high... Read More
National Center for Interpretation Navajo Legal Training and Testing Materials: 1993-2013
ua15-006 – The Navajo training materials encompass presentations, scripts, glossaries, and manuals to enable prospective Navajo candidates to master all aspects of interpretation in a legal setting. This includes ethics, standards, and protocol; specialized legal and medical terminology; strategies of consecutive, sight, and simultaneous interpretation, skills-based practice and evaluation using a... Read More
Interactive Self-Study iBook for Spanish-English Interpreters
ua14-142 – Interactive Self-Study iBook for Spanish-English Interpreters. Background: This product is designed to help improve the proficiency skills of Spanish-English interpreters, specifically those working in a judicial context. It likewise helps Spanish-English interpreters that are preparing for the Federal Court Interpreter Certification Examination (FCICE). This self-study iBook contains... Read More
Geometry for Parents, a Math for Parents Mini-Course (Book), Copyright 2007 ABOR
ua14-141 – Background NSF funded MAPPS, a project to develop activities and materials to engage the parents of school-age children in the mathematics of the schools. One set of activities developed consisted of mini-courses; Geometry for Parents is one of these. Each mini-course consists of 8 two-hour sessions for parents participants. The book is a guide for individual(s) facilitating the mini-course,... Read More
SkyView App
ua14-137 – SkyView is an interactive digital magazine for iPad created by the University of Arizona’s School of Journalism. The magazine is a successor to our inaugural digital publication the Scientific Tucsonan. SkyView explores the wealth of science and nature found in the Santa Catalina Mountains, just north of Tucson, Arizona. The magazine features ten articles packed with stories, interactive... Read More
Identification of Endohyphal Bacterial Symbionts as Major Determinants of Cellulase and Ligninase Activity in Fungi
ua14-149 – Plant-associated fungi play important ecological roles as pathogens, mycorrhizae, endophytes, and saprotrophs. As endophytes, Fungi colonize healthy, living plant tissues, providing protection from pathogens, herbivores, and other environmental stressors such as drought. As saprotrophs, Fungi are the primary decomposers of senescent plant materials, breaking down both lignin and cellulose,... Read More
Exploiting Novel Pseudomonas Syringae Bacteriocins as Antibacterials
ua14-107 – This invention relates to a method of controlling phytopathogens through bacteriocin-mediated inhibition of bacterial plant pathogens. This method reduces the number of bacteria found on the surface of a plant. Specifically, this invention relates in one embodiment to Pseudomonas syringae (P. syringae) strains tailored to controlling phytopathogens. Pseudomonas syringae (P. syringae)... Read More
Enhancing the Sugar, Starch, and Cellulose Content in Plants
ua14-047 – This technology comprises an approach to “fool” the whole plant or targeted tissues of the plant to perceive low nitrogen status. The goal is to induce the plant to remodel its growth into increasing the ratio of carbon to nitrogen via reprogrammed metabolism. By genetically manipulating the plant’s perception of nitrogen status, and therefore apparent nitrogen availability, it is feasible... Read More
A Vector System for Direct Cloning of Eukaryotic Gene Constructs
ua13-093 – YAB (for Yeast-Agrobacterium-Bacteria) is a combination of two technologies: Yeast recombination capabilities and ATMT. Generation of ATMT constructs usually requires PCR-amplification of DNA fragments and multiple cloning steps into binary Agrobacterium vectors. YAB is a plasmid vector that can be used to combine in one single step several kinds of DNA fragments using the yeast... Read More
Holographic Binocular Adaptive See-Through Phoropter
ua12-039 – Researchers at the University of Arizona have created a holographic, binocular adaptive transmissive phoropter. This new design can measure spherical and cylindrical error and then null the error through a sphero-cylindrical fluidic lens system. Holographic or diffractive elements are used to collect light scattered from an eye of the viewer and image the scattered light to the wavefront... Read More
Buttressed Haptic Design for Accommodating Intraocular Lens
ua13-013 – The following invention is a buttressed haptic that actuates the mechanically accommodating intraocular lens from the eye’s ciliary muscle. The technology allows the eye to change its focal distance using the eye’s natural mechanism of ciliary body muscle tension. The haptic receives radial tension from relaxation of the ciliary muscle to provide anterior vectored force on the lens,... Read More
Automated Robotic Heat Exchanger Tube Cleaning and Inspection Machine
ua14-185 – This invention consists of an automated machine to clean each individual tubes on a chiller condenser barrels with minimal operator input. The invention works by mounting a typical manual tube punching device onto a mobile frame, which utilizes imaging technology to determine the location and accessibility of a tube. It then automatically maneuvers the punching device in place, cleans the... Read More
From Ancient to Modern Southwest Indian Pottery App
ua14-006 – Get up-close and personal with four Southwest pottery masterworks from the Arizona State Museum Pottery Project! This interactive app lets you spin and look inside pots dating from 1200 - 2009 CE (AD) while providing historic and cultural context. Of interest to casual art enthusiasts and experts alike, the richly illustrated app features an ancient Mesa Verde Black-on-white mug; a Fourmile... Read More
UAbacus App
ua14-017 – With the UAbacus you can add and subtract numbers using the “logic method” for abacus computation. Those learning abacus computation can practice their computation skills getting help with a step if they become stuck and having the correct answer verified. Users who do not know how to compute using a Cranmer abacus using the logic method can support individuals who are abacus users by... Read More
Scientific Tucsonan
ua14-128 – The University of Arizona’s School of Journalism has created an iPad application that produces a virtual multimedia magazine filled with student’s works in the area of science and technology. The application is an interactive magazine allowing the user to sift through articles, photos, videos, and info-graphics about Arizona science and technology. The Scientific Tucsonan is intended to... Read More
Arizona's Economy Application for I-Phone, I-Pad, and Android
ua14-055 – This Interactive phone and tablet application extends the reach, accessibility, and timeliness of the socio-economic indicator data the University of Arizona Economic and Business Research Center (EBR) offers to the citizens of Arizona and the world. This phone and tablet application allows users to access real-time data pertaining to Arizona, Its counties and metro areas by data topic and by... Read More
The University of Arizona College of Fine Arts Viewbook App
ua14-010 – This app has been developed for prospective students. The College of Fine Arts at the University of Arizona consists of four professional schools: The Schools of Art, Dance, Music and the newly redesigned School of Theatre, Film, and Television. In addition, five professional organizations provide excellent resources for students. You can download the app from iTunes.
Arizona Alumni Magazine for the iPad App
ua13-108 – Awaken your inner Wildcat for Life! Download The Arizona Alumni Magazine App on your iPad. It’s free for all and includes all of the content you’ve come to enjoy from the print edition plus special interactive features. Touch, tap, and swipe your way through iPad-only photo galleries. Pinch and zoom old photos of campus. Watch short videos and audio slide shows. Learn what’s happening on... Read More
School of Theatre, Film and Television App
ua14-051 – The School of Theatre, Film & Television at The University of Arizona offers our students a comprehensive education in the art and business of storytelling. With extremely active production programs and an exceptionally talented faculty of professional working artists, students study and learn in a creative and professionally focused environment. This app features our talented and... Read More
Dr. Sakles' Airway CQI Form
ua14-170 – Invention The Airway CQI form is a data collection form used to track intubation practices performed in the Emergency Department at the University of Arizona Medical Center. The purpose of the form is to collect pertinent data on emergency intubation activities and use the data as a CQI tool to improve the care delivered to patients. Background When dealing with medical practices,... Read More
A Memory Assessment for Preschool-Aged Children and Special Populations
ua14-179 – Title: System and Method for Neuropsychological Assessment for Young Children and Special Populations Invention: The present invention is a neuropsychological assessment test of different memory processes which access the medial, temporal, neural and the prefrontal cortex regions of the brain. It is currently the only comprehensive test for memory and learning designed for children under... Read More
Stabilized Black Lipid Membranes Prepared via Polymer Scaffolding
ua14-172 – Invention This invention presents a new approach for stabilizing BLMs relying on inexpensive commercially available materials. Here, a method is employed that chemically modifies the lipid membrane to dramatically improve BLM stability. Background Black lipid membranes (BLMs), are synthetic membranes used to measure ion channel activity. Suspended Lipid Membranes, BLMs, provide a key... Read More
Polymerization of Lipid Assemblies in Aqueous Solution at Neutral pH
ua14-171 – The present invention provides compounds comprising a triazenylidene moiety and methods for producing and using such compounds Technology Background: Normally, polymerization of lipids involves the production of acidic side products (Srisiri 4866). Acidic conditions usually compromise protein bioactivity, rendering them useless when combined with the polymer. Invention: The invention... Read More
Synthesis of Chiral 3-Pyrrolines via an Anionic Annulation Approach
ua15-004 – Technology Background: There are seven main types of anti-hypertensives on the market now. The invention can help create either direct acting vasodilators or direct renin inhibitors. Invention: Invention consists of a novel method to access chiral 3-pyrroline products in one step. The treatment of a gamma leaving group with a strong base results in an anion. That anion can then be... Read More
Method for Detecting Iron-Specific Hypercoagulation
ua14-105 – This technology is a novel method for detecting clotting parameters related to iron-specific hypercoagulation in settings such as sickle cell disease, hemodialysis, mechanical circulatory support and repeated blood transfusions. Iron-mediated hypercoagulation is the result of increased plasma concentrations of iron. Utilizing information about the underlying molecular mechanisms of... Read More
Improvements Over Existing Methods/Devices/Materials Related to the Discovery of Novel Multivalent/Multifunctional Ligands With Agonist Activities at Opioid Receptors and Antagonist Activities at Nk-1 Receptor for the Treatment of Pain and Other Indi
ua14-103 – The invention describes a new ligand that has a very specific structure. It is cyclic in nature, making it more bioavailable, stable, and active in vivo. Furthermore it is comprised of unnatural amino acids, this confers specificity for NK-1 receptors. The compound antagonizes these receptors and makes them unavailable for use. It can be used as both an anti-inflammatory compound and an... Read More
A Gi-Specific Contrast Agent for Magnetic Resonance Imaging
ua12-105 – Background: Gastrointestinal (GI) radiography using barium contrast media has been widely used as a first-choice diagnostic imaging modality for detection of GI pathologies. Colonoscopy is the standard of care for colorectal cancer (CRC) screening. However, colonoscopy is an invasive procedure that requires intravenous sedation and suffers from patient noncompliance. CT colonography (CT-C)... Read More