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Cultured Cells Lifting/Cryopreservation Efficiency Training Program
This is an innovative spreadsheet-based method designed to improve the efficiency of training and evaluation for cultured cell lifting and cryopreservation procedures. It is part of a comprehensive training program aimed at streamlining skill acquisition in cell culture labs. Unlike traditional methods, where training outcomes are evaluated broadly...
Published: 4/22/2025
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Inventor(s): Chi Zhou
Keywords(s):
Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Software & Information Technology > Education & Training
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Battery-Free Wireless Epidermal Sensor Networks for Continuous and High-Fidelity Systolic Blood Pressure Monitoring
This invention is a wireless, battery-free system of epidermal sensors designed for continuous and high fidelity monitoring of physiological signals, such as blood pressure. The system eliminates the need for batteries by using a smartphone to wirelessly deliver power to the sensors and collect biosignals. The sensors are designed to function seamlessly...
Published: 12/17/2024
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Inventor(s): Philipp Gutruf, Kevin Kasper, Selman Kurt, S. Y. John Ho
Keywords(s):
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Communications & Networking > Wireless, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Sensors & Controls
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StellarScape - Immersive Multimedia Performances, Experiences, and Installations
StellarScape is a combination of music, dance, and cinematography, blended with state-of-the-art data visualization and astrophysical simulation. StellarScape is not only an immersive multimedia performance synthesizing music, science, visual art, and technology, but also an interactive audiovisual installation/experience that allows the visitors to...
Published: 10/25/2023
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Inventor(s): Yuanyuan He, Winslow Burleson, Christopher Impey
Keywords(s):
Category(s): Technology Classifications > Creative Works, Technology Classifications > Software & Information Technology > Computer-Aided Design & Engineering, Technology Classifications > Sensors & Controls > Motion & Force, Technology Classifications > Software & Information Technology
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Allosteric Inhibitors of the Main Protease of SARS-CoV-2
In this report, the SARS-CoV-2 3CLpro was expressed and purified. By using a FRET-based enzymatic assay, the researchers have screened a library consisting of more than 300 different niclosamide derivatives and identified three molecules JMX0286, JMX0301, and JMX0941 as potent allosteric inhibitors against SARS-CoV-2 3CLpro, with IC50 values like that...
Published: 4/1/2024
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Inventor(s): Hongmin Li, subodh samrat, Zhong Li, Jia Zhou, Jimin Xu
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Infectious Diseases
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Combinations for the Treatment of Neurodegeneration
Researchers at the University of Arizona have researched new formulations and combinations of compounds for the treatment of Alzheimer’s disease. Developing a novel computational system allowed the inventors to identify several therapeutic targets of single cell type and whole bulk tissue that contribute to Alzheimer's disease. These therapeutic...
Published: 4/3/2023
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Inventor(s): Rui Chang, Patrick Ronaldson, Wei Wang, Vijayan Ramachandran, Yanyun Liu, Qianying He
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Life Sciences
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Stem Cell Fusion Model of Carcinogenesis
This technology is a method for modeling cancer cell migration, screening drugs for effects on tumor cell migration, and detecting the potential for tumor cell migration relating to the fusion of a bone marrow derived stem cell with a genetically altered cell.
Background:
Cancer has been difficult to treat because of tissue heterogeneity and gene instability....
Published: 4/3/2023
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Inventor(s): David Harris, Tom Tsang, Brian Pipes, Xianghui He
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Stem Cells
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Conjugation of the MCR1 Ligand with Cytotoxic Drugs for Targeted Melanoma Therapy
University of Arizona researchers have developed a drug composition and method of cancer treatment using chemotherapeutics linked to ligands selective for uptake by melanocortin 1 receptors (MC1R) in MC1R-overexpressing melanoma. This development targets melanoma, and may be used with a wide range of cytotoxic drugs, to selectively deliver a toxic payload...
Published: 3/12/2024
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Inventor(s): Minying Cai, Victor Hruby, Yang Zhou
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Healthcare Portfolios > Oncology
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Enzymatically Released Aryl Diazonium Ions
This invention is the discovery of triazebutadienes that rapidly release aryl diazonium ions at neutral pH with a half-life of approximately one minute.
Background:
In 2015, the global protein therapeutics market grew to nearly $174.7 billion due to trends in targeted therapies that resulted in fewer side effects. Monoclonal antibodies and biologics...
Published: 12/5/2024
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Inventor(s): John Jewett, Lindsay Guzman, Bereketab Mehari, Jie He
Keywords(s):
Category(s): Technology Classifications > Life Sciences
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Reactive Oxygen Species Gene Signature Predicts Survival in Sepsis
This technology is a 21-gene reactive oxygen species (ROS)-associated molecular signature that predicts survival in septic patients. This particular signature has outperformed randomly generated signatures of the same signature gene size. This signature is easily assayed from peripheral blood and can potentially predict.
Background:
There is a significant...
Published: 11/16/2023
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Inventor(s): Louise Hecker, Marvin Slepian, Christian Bime, Tong Zhou, Nima Pouladi, Ting Wang
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics
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Early Assessment of Biophysical Parameters Predicts Lesion Formation During RF Energy Delivery
Lesion size or volume prediction shortly after the beginning of an ablation procedure can inform and/or control the ablation process. The prediction and/or control is made without regard to an actual detected temperature in the vicinity of the ablation electrodes. As a consequence, the system has utility with irrigated catheter constructions and other...
Published: 4/3/2023
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Inventor(s): Frank Marcus, Michael Bosnos, Ding Sheng He, José Guillén-Rodríquez
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic
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