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Angle-Resolved Second Harmonic Generation Measurements for Cancer Diagnosis in Semi-Infinite Tissue

This innovation is a new method that uses angular differences in conjunction with an endoscope to identify cancerous or pre-cancerous colon tissue. Existing methods require a reference measurement ('normal') in every patient compared to a cancer-suspicious measurement. Instead, this method and endoscope provide for angle-resolved second harmonic...

Published: 11/13/2023 | Inventor(s): Jenna Montague, Jennifer Barton

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Category(s): Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Imaging & Optics > Medical Imaging

Non-Imaging, Random-Sampling Second Harmonic Generation Measurements to Distinguish Colon Cancer

Second-harmonic generation (SHG) microscopy has emerged as a powerful modality for imaging fibrillar collagen in a diverse range of tissues. A preliminary study demonstrated that non-imaging, randomly sampled SHG intensity measurements are likely sufficient to distinguish normal colorectal tissue from tumor/tumor-adjacent tissue with digital simulation...

Published: 4/3/2023 | Inventor(s): Jenna Montague, Jennifer Barton, Hasina Shir

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Oncology