Search Results - pawel+laniewski

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Metabolic Screening Methods for Endometrial Cancer
Researchers at the University of Arizona employed cervicovaginal lavage sampling and a global untargeted metabolomic approach to identify potential biomarkers for endometrial cancer. The study's novel approach involved linking cervicovaginal metabolite levels to crucial tumor characteristics such as size, histological grade, and myometrial invasion,...
Published: 3/1/2024   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
Phenyllactic Acid: Antimicrobial Activity against Vaginal Microbiota and Cytotoxic Properties on Human Cervical Epithelial Cells
Researchers at the University of Arizona investigated the antimicrobial properties of Phenyllactic Acid (PLA) derivatives against both commensal and Bacterial vaginosis (BV)-associated bacteria, as well as their cytotoxic effects on human cervical epithelial cells. PLA is a broad-spectrum antimicrobial compound produced by vaginal Lactobacillus species;...
Published: 1/16/2024   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski, Abhijit Date, Phoebe Crossley
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Infectious Diseases
Methods for Guiding Treatments of Vulvovaginal Symptoms and Female Sexual Dysfunction
Multi-omics analysis of cervicovaginal samples has led to the identification of a specific immune mediators, metabolites, and bacteria that are associated with vulvovaginal and sexual health symptoms. These biomarkers hold the potential to be utilized in a non-invasive test that guides the treatment of vulvovaginal symptoms and female sexual dysfunction...
Published: 6/6/2024   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Therapeutics
Diagnostic for Non-Invasive Screening and Early Detection of Adenomyosis
This technology is a non-invasive diagnostic for the screening and detection of adenomyosis. This could be used for women who are suffering with symptoms of chronic pelvic pain and adenomyosis for diagnosis without an invasive hysterectomy. In preliminary studies, there have been high acceptance of a particular sampling, that can provide information...
Published: 6/6/2024   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Women's Health
Diagnostic for Screening and/or Predicting Women "at risk" for the Development and Progression Endometrial Cancer
This invention describes a novel method to use metabolic markers in samples obtained from cervicovaginal lavage (CVL) and machine-learning algorithms to detect patients “at risk” for endometrial cancer (EMC). Background: Endometrial cancer (EMC) is the most common gynecological cancer. The American Cancer Society estimates that in 2021...
Published: 11/16/2023   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Women's Health
Diagnostic for Monitoring Response to Immunotherapies for Gynecologic Cancer
This invention is a collection of immunological checkpoint proteins and physiological markers to diagnose and potentially monitor treatments for cervical cancer. This biomarker panel would be taken using the cervicovaginal lavage method, which is less invasive than other sampling methods for cervical cancer. This diagnostic test could be used not only...
Published: 6/6/2024   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics