Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
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Inventor(s): Leilei Peng, Yu Li, Han Zhang
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
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Novel Inhibitors of GAB1
The compounds discovered in this patented technology could be used as a breast cancer therapeutic drug.
There are a few call signaling pathways that are heavily involved in the pathogenesis of cancer. Two of these pathways are the RAS pathway and the PI3K pathway, and both of these pathways are deregulated in the formation of human cancer. This...
Published: 4/3/2023
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Inventor(s): Emmanuelle Meuillet, Lu Chen, Shuxing Zhang
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Small Molecules
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Targeting the PH/DH Domain of Tiam1 for the Treatment and/or Prevention of Bone Metastases
Tiam1 is a highly conserved exchange factor that is over-expressed in many cancers, including prostate cancer (CRPCA). Increase in Tiam1 expression is associated with increased metastases and correlates with poor PCA patient survival prognosis. This patented technology has identified a novel compound which exhibits the ability to reduce prostate cancer...
Published: 4/3/2023
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Inventor(s): Emmanuelle Meuillet, Sylvestor Moses, Shuxing Zhang
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Small Molecules
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