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Compressing Ion-Beam Shutter
The compressing ion-beam ion shutter developed at The University of Arizona is composed of a series of electrically charged screens. By varying the relative voltages on the screens, the flow of ions into the detector chamber is blocked or opened. When the shutter is first opened, ions accumulate between the screens. When the shutter voltage is changed,...
Published: 7/15/2022   |   Inventor(s): Roger Sperline
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
Surface-Modified Electrospray Needles for Mass Spectrometry
With this invention, electrospray needles used in mass spectrometry are coated to prevent sticking and clogging of analytes, resulting in improved mass detection sensitivity and consistency of analysis. The coating comprises an organic material covalently bonded to an interior surface of the electrospray needle. The coating is electrically non-conductive...
Published: 7/15/2022   |   Inventor(s): Michael Marty, Craig Aspinwall, Marius Kostelic, Chih-Chieh Hsieh
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Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Microfluidics, Technology Classifications > Materials > Coatings
Deconvolution of Charge Detection-Mass Spectrometry Data
This mass spectrometry analysis software and method extends the UniDec Bayesian deconvolution algorithm for application to two-dimensional charge detection-mass data. A 2D plot of m/z versus charge is created from raw data. Smoothing and background subtraction may be used, and deconvolution is applied to remove uncertainty in the charge and the m/z...
Published: 7/15/2022   |   Inventor(s): Michael Marty, Marius Kostelic
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Category(s): Technology Classifications > Life Sciences, Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
Eliminating deconvolution artifacts with softmax function
This invention is mass spectrometry analysis software which uses a SoftMax function to adjust the relative charge state assignment which takes place during deconvolution. This approach removes deconvolution artifacts. Background: Mass spectrometry (MS) and intact mass analysis are increasingly common in academic and industry research. This has created...
Published: 7/15/2022   |   Inventor(s): Michael Marty
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Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
Micro Faraday-Element Array Detector for Ion Mobility Spectroscopy
The novel ion mobility spectrometry (IMS) includes a drift tube having a collecting surface covering a collecting area at one end of the tube. The surface comprises a plurality of closely spaced conductive elements on a non-conductive substrate, each conductive element being electrically insulated from each other element. A plurality of capacitive transimpedance...
Published: 7/15/2022   |   Inventor(s): M Denton, Roger Sperline, Christopher Gresham, Phillip Rodacy
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Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry
Differential Transimpedance Amplifier Circuit for Correlated Differential Amplification
Researchers at the University of Arizona have created a differential transimpedance amplifier circuit for correlated differential amplification. The amplifier circuit increases electronic signal-to-noise ratio in charge detection circuits designed for the detection of very small quantities of electrical charge and/or very weak electromagnetic waves....
Published: 7/15/2022   |   Inventor(s): M Denton, Roger Sperline, Christopher Gresham
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Mass Spectrometry