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Sugar-Based Low Molecular Weight Hydrogels from Alkyl Glycolipids
University of Arizona researchers have created sugar-based low molecular weight hydrogels that spontaneously self-assemble through weak, noncovalent intermolecular interactions. These gels are thixotropic, biocompatible, and biodegradable. Despite being held together through non-covalent interactions, these hydrogels exhibit greater mechanical strength...
Published: 3/26/2021   |   Inventor(s): Jeanne Pemberton, Laurel Kegel, Yu-Cheng Wang
Keywords(s):  
Category(s): Technology Classifications > Energy, Cleantech & Environmental > Remediation, Technology Classifications > Engineering & Physical Sciences > MEMS & Nanotechnology, Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone, Technology Classifications > Healthcare Portfolios > Regenerative Medicine / Tissue Engineering, Technology Classifications > Healthcare Portfolios > Wound Healing, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Materials > Biocompatible, Technology Classifications > Materials > Biomaterials, Technology Classifications > Materials > Medical Devices > Therapeutic, Technology Classifications > Materials > Nanomaterials
Topical Delivery of Natural Tanning Active Ingredient for Melanoma Prevention Using Peptides Selective for Melanocortin Receptor 1
This invention is the topical delivery of a natural peptide ingredient to aid in the production of melanin without exposure to UV radiation. The product is stable and selective for the human melanocortin-1 receptor (hMC1R), avoiding off-target effects with non-selective melanocortin ligands. Background: Melanoma is the most dangerous form of skin...
Published: 9/21/2020   |   Inventor(s): Minying Cai, Victor Hruby
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Dermatology
Photochemically Stable, Non-Leaching, Bridged Polysilsesquioxane Based Sunscreens
This technology is a non-toxic, long-lasting sun protection based on nanoparticles of bridged polysilsesquioxanes. Background: UV radiation (100 – 400 nm) represents ~10% of electromagnetic radiation (sunlight) that reaches the Earth's surface, and can be separated into three main types: UVC (100 – 290 nm), which has the shortest...
Published: 9/15/2020   |   Inventor(s): Douglas Loy, Stephanie Tolbert
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Materials > Nanomaterials, Technology Classifications > Materials > Polymers
Sunscreens Based on Phenolic-Formaldehyde Particles
Sun-protective polymeric particles using a micro emulsion polymerization by nucleation approach have been developed by researchers at the University of Arizona. The resulting resorcinol-formaldehyde is red to brown in color with strong absorption of UVA and UVB radiation, making it an ideal material for sunscreen. Resorcinol-formaldehyde has been widely...
Published: 9/15/2020   |   Inventor(s): Douglas Loy, Robb Bagge, Nanayakkarawasan Pallage Nanayakkara
Keywords(s): nano-particles
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology
Sunscreens Prepared from Polydopamine and Poly (dopamine-co-cafeic acid)
This invention is synthetic eumelanin particles prepared by polymerization of dopamine that can be dispersed in water, glycerol or oil. Background: Sunscreen products in the market today are typically made of potentially harmful chemicals, including avobenzone, which releases cancer-causing free radicals, and oxybenzone, which has estrogenic properties...
Published: 9/15/2020   |   Inventor(s): Douglas Loy, Robb Bagge, Nanayakkarawasan Pallage Nanayakkara
Keywords(s): nano-particles
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology
New Sunscreens Based on Particles Prepared from Higher Aldehydes and Phenols
This invention consists of particles that can be used as sunscreens prepared by the copolymerization of phenols with aromatic and conjugated aldehydes like cinnamaldehyde or benzaldehyde. These particles made of bio-based materials can be dispersed in liquid and function as thermosets for sun-blocking purposes. Background: Sunscreen products in the...
Published: 9/15/2020   |   Inventor(s): Douglas Loy, Robb Bagge, Nanayakkarawasan Pallage Nanayakkara
Keywords(s): nanoparticles
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology
Targeted Therapy for Itch
TMEM184B is a relatively uncharacterized 7-pass transmembrane protein that is a member of the Transporter-Opsin-GPCR (TOG) superfamily of proteins. It was discovered that over-expression of TMEM184B caused a reduction in scratching in response to interleukin-31 (Il-31) exposure. This was surprising given previous studies had shown that knock-out of...
Published: 1/27/2020   |   Inventor(s): Martha Bhattacharya, Tally Largent-Milnes
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Life Sciences > Therapeutics
Conjugation of the MCR1 Ligand with Cytotoxic Drugs for Targeted Melanoma Therapy
University of Arizona researchers have developed a drug composition and method of cancer treatment using chemotherapeutics linked to ligands selective for uptake by melanocortin 1 receptors (MC1R) in MC1R-overexpressing melanoma. This development targets melanoma, and may be used with a wide range of cytotoxic drugs, to selectively deliver a toxic payload...
Published: 7/22/2019   |   Inventor(s): Minying Cai, Victor Hruby, Yang Zhou
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Healthcare Portfolios > Oncology
Biomarker to Assess Risk For Skin Cancer Development
This technology is a diagnostic test that can help assess a patient's risk for developing skin cancer by measuring biomarker levels under specified conditions. Additionally, the test can help determine prophylactic treatment for an individual at risk of developing skin cancer. Background: Skin cancer is the most common type of cancer among the...
Published: 12/10/2018   |   Inventor(s): Clara Curiel, Amanda Fern Baker, Sally Dickinson, Emmanuel Petricoin III
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
Dihydropyridazine Antioxidant Sunscreen that Signals Depletion with Bleaching of Fluorescence
This invention is a UVA and UVB absorbent with dihydropyridazine purposed to act as a sunscreen antioxidant. Background: Commercial sunscreens, which aim to prevent the development of skin cancers and melanoma, compete to minimize UV damage while allowing user to apply on either dry or wet skin. Unfortunately, it is difficult to effectively gauge...
Published: 10/9/2017   |   Inventor(s): Douglas Loy, Robb Bagge
Keywords(s):  
Category(s): Technology Classifications > Materials, Technology Classifications > Healthcare Portfolios > Dermatology
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