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Acoustic Radiation Force Impulse Procedures for Modulating Glial Cells and Neurons in the Central Nervous System
This technology leverages focused ultrasound and Acoustic Radiation Force Impulse (ARFI) techniques to improve brain health by normalizing synaptic activity and enhancing waste clearance in the central nervous system. It provides two non-invasive procedures: one targets astrocytes to modulate synaptic activity, while the other stimulates the glymphatic...
Published: 3/24/2025
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Inventor(s): Nan-kuei Chen
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Sensors & Controls > Motion & Force, Technology Classifications > Medical Devices > Therapeutic
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Intracranial and Cerebrospinal Fluid Deuteration using Heavy Water Isotopologues
This invention is a method of therapeutic intervention for primary and metastatic brain cancer, and other relevant nervous system derivates, via the deliverances of deuterated heavy water isotopologue. This novel treatment method offers promise for specificity improvements as it uses water to deliver its therapy, allowing for increased efficiency in...
Published: 3/3/2025
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Inventor(s): Georg Wondrak, Jana Jandova
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Therapeutics
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Organ-on-Chip Apparatus for Quantitative Study of Cellular Interaction with Ultrasound
This is an organ-to-chip device that is constructed by using thin membranes. The device allows quantitative in vitro modeling of cellular interactions by using ultrasound. The technology also has a large potential for therapeutic applications for treating different diseases. The flexibility of organ-on-chip technologies is a great tool to help speed...
Published: 11/6/2024
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Inventor(s): Jian Gu, Adam Akkad, Frederic Zenhausern
Keywords(s):
Category(s): Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences
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Myelin Breakdown Products as Plasma Biomarkers of Therapeutic Efficacy in the Acute Phase after Stroke
This invention pertains to the use of myelin breakdown products, such as lipids indicative of brain lipid catabolism, as plasma biomarkers for the diagnosis and prognosis of ischemic stroke (IS). Researchers discovered an acute signature of brain lipid catabolism in the plasma 24 hours after a stroke in mouse model research. Notably, a substantial proportion...
Published: 8/12/2024
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Inventor(s): Kristian Doyle, Danielle Becktel
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Biomarkers
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Arachidonic Acid Derivatives as Plasma Biomarkers of Chronic Inflammation After Stroke
This invention pertains to the use of arachidonic acid derivatives as plasma indicators for the diagnosis and prognosis of inflammation, including chronic inflammation, following ischemic stroke (IS). Researchers have identified novel plasma biomarkers indicative of neurodegeneration and inflammation in a mouse model of stroke, with particular emphasis...
Published: 8/12/2024
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Inventor(s): Kristian Doyle, Danielle Becktel
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Biomarkers
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Stroke Outcome Prediction Using Vascular Imaging Features and Machine Learning
This technology is a stroke outcome prediction method to determine patient outcomes and inform treatment decisions. The method utilizes machine learning models trained with patient-specific vascular imaging features, patient demographics, stroke severity scores and clinical history as predictors to forecast a 90-day functional outcome following an ischemic...
Published: 4/28/2025
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Inventor(s): Aditi Deshpande, Kaveh Laksari, Jordan Elliott, Pouya Tahsili-Fahadan
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences
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Smart EVD System
This invention is a smart system for the collection of cerebrospinal fluid from an external ventricular drain (EVD) that can automatically adjust the height and intercranial pressure of a patient. The invention will use a cerebrospinal fluid (CSF) flow sensor, a way to determine the position of the patient and the collection vessel, and an actuator...
Published: 8/1/2024
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Inventor(s): Eniko Enikov, Jesse Skoch
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Medical Devices
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Optical and Acoustic Coupling Materials and Technologies
This invention describes materials and chemicals with novel, optimal optical and acoustic properties that enable or improve methods that require coupling of light and sound for biomedical and defense applications related to imaging and monitoring therapy. This invention overcomes current limitations by proposing optically and acoustically transparent...
Published: 2/28/2025
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Inventor(s): Russell Witte, Christopher Salinas, Eric Reichel
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Research Tools, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences
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Glycopeptide-Lipid Supramolecular Assembly
This invention provides an approach, including compositions and methods for delivering glycopeptides to biological cells. This is done using supramolecular assemblies made of glycopeptides and amphipathic molecules, which may be used to deliver therapeutics, including glycosylated hormones or their analogues, such as endomorphin, dermorphin, angiotensin,...
Published: 6/20/2024
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Inventor(s): Robin Polt, Michael Heien
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Neurology
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Neonatal Anorectal Tonometer with Disposable/Detachable Tip
This technology is a neonatal anorectal tonometer that involves a detachable, fluid-filled tip with a quick release system involving (magnet & plate) that connects the tip to a force sensor inside the handle of the device. This device can be used as a substitute for digital rectal exams.
Background:
Cauda Equina Syndrome (CES) occurs when the Cauda...
Published: 8/1/2024
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Inventor(s): Eniko Enikov
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Emergency Medicine, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Sensors & Controls, Technology Classifications > Sensors & Controls > Motion & Force
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