Search Results - technology+classifications+%3e+healthcare+portfolios+%3e+neurology+%3e+cns+%26+neurosciences

23 Results Sort By:
Neonatal Anorectal Tonometer with Disposable/Detachable Tip
This technology is a neonatal anorectal tonometer that involves a detachable, fluid-filled tip with a quick release system involving (magnet & plate) that connects the tip to a force sensor inside the handle of the device. This device can be used as a substitute for digital rectal exams. Background: Cauda Equina Syndrome (CES) occurs when the Cauda...
Published: 1/26/2023   |   Inventor(s): Eniko Enikov
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Emergency Medicine, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Sensors & Controls, Technology Classifications > Sensors & Controls > Motion & Force
Stroke Outcome Prediction using Vascular Imaging Features
This is a prediction method to determine the outcome of a stroke based on vascular images presented by the patient. This model predicts the 90-day functional outcome after ischemic stroke at a significantly higher accuracy than current models, to inform treatment decisions and patient selection. Machine learning models were employed and trained with...
Published: 12/8/2022   |   Inventor(s): Kaveh Laksari, Aditi Deshpande, Jordan Elliott, Pouya Tahsili-Fahadan
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Diagnostics
Method for Diagnosing, Imaging, and Treating Overwhelmed Myelin Lipid Processing within Immune Cells in the Brain After Stroke
It was discovered that foam cells form within primary infarcts and areas of secondary neurodegeneration after stroke. This invention provides for a method of noninvasive imaging and assessment of fatty acid oxidation in the brain after stroke using radionuclide and magnetic resonance-based imaging currently used to measure myocardial fatty acid oxidation...
Published: 11/8/2022   |   Inventor(s): Kristian Doyle
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Diagnostics
Treating or Preventing Anorexia Nervosa via Precision Targeting of Neuronal Circuit
­This invention provides methods of treating one or more eating disorders, including anorexia nervosa, bulimia, and related clinical syndromes. A new treatment strategy has been discovered, comprising inhibiting two different neural circuits, which rescues all three of the activity-based anorexia (ABA) animal model phenotypes of extreme increases...
Published: 11/8/2022   |   Inventor(s): Haijiang Cai, Wesley Schnapp
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Neurology > Mental Health, Technology Classifications > Life Sciences > Therapeutics
Synapse Surgery Tools for Neural Circuit-Specific Synapse Ablation and Modification
Researchers at the University of Arizona have developed novel synapse manipulation tools, so called synapse surgery tools, using the endogenous synapse pruning system. Complement proteins tagging system for target synapses are effective in eliminating specific synapses relevant to neuronal functions and diseases. To accomplish this, the technology is...
Published: 11/21/2022   |   Inventor(s): Deveroux Ferguson, Hee-Dae Kim
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Research Tools
Tetrazolium-Based Pro-Chelators as New Anticancer Agents
This invention comprises a class of tetrazolium-based prochelators for targeting and binding intracellular iron for selective cancer cell antiproliferation or other iron dysregulation. Various analogues within this class of chemistry can be tuned to the redox potential for selective targeting of cancer cell types. Background: Iron is an essential...
Published: 1/19/2023   |   Inventor(s): Elisa Tomat, Zoufeng Xu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences
MC4R Selective Ligand for Obesity and Alzheimer’s Disease Prevention
This technology is a novel peptide that has been shown to be a potent MC4R selective antagonist. It is a potential therapeutic for cognitive loss and obesity. Background: The challenges of neurodegradation, Alzheimer’s disease, and obesity have been shown to have some similar molecular signatures that contribute to disease and have thus created...
Published: 9/26/2022   |   Inventor(s): Minying Cai, Victor Hruby
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
Small Molecule Mixed Agonist/Antagonist for Opioid Receptors for Anti-Addiction and/or Pain Therapy
This invention provides compositions and method of pain treatment using a mixture of an opioid receptor agonist in combination with an adrenoreceptor modulator compound. The opioid receptor agonist may be a clinically-used drug, and the adrenoreceptor modulator compound is a novel small molecule. ­Proof-of-concept testing in animals has shown...
Published: 7/15/2022   |   Inventor(s): Iman Daryaei, John Streicher, Abigail Schwarz
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
Novel Small Molecule Compounds with Neuroprotective Potential in ALS and Related Neurodegenerative Diseases
This invention comprises a series of novel small molecule compounds developed at the University of Arizona and their method of use for the treatment of locomotor dysfunction associated with Amyotrophic Lateral Sclerosis (ALS) and other diseases associated with proteinopathy of a transactive response (TAR) DNA binding protein, TDP-43. Testing in a previously...
Published: 8/17/2022   |   Inventor(s): Daniela Zarnescu, Jon Njardarson, Isaac Chogii, David Smith, Edon Vitaku, Rachel Allen
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Therapeutics
Neuroprotection via Glycosylated PACAP Analogues with Differentiated Selectivity toward PAC1 and VPAC1 > VPAC2
Inventors at the University of Arizona have developed glycopeptide analogues of PACAP which exhibit selective PAC1 and/or VPAC1 receptor activity with a reduced VPAC2 receptor activity as compared to native PACAP, an endogenous peptide hormone associated with neuronal tissue repair. Thus, these compounds have positive benefits of PAC1 and VPAC1 activation...
Published: 7/15/2022   |   Inventor(s): Robin Polt, Parthasaradhi Reddy Tanguturi, Christopher Apostol, John Streicher, Lajos Szabo
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
1 2 3