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This technology is a novel method of phase unwrapping that improves the accuracy of existing fast unwrapping techniques through revising transform coordinates. Background: Phase maps have a variety of uses, from medical diagnosis including magnetic resonance imaging (MRI) to interferometric surface characterization in manufacturing and synthetic aperture...

Published: 5/8/2023 | Inventor(s): Pierre Blanche, Pedro Alcaraz, Remington Ketchum

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Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

A Gamma-ray Photon Counting Detector Based on Side-readout of Monolithic Scintillator Layers

Researchers at the University of Arizona have developed a gamma-ray photon counting device that works similarly to PET, but with a novel architecture that improves the accuracy and speed in determining the location of the biological targets, and is less costly to manufacture. Background: Positron Emission Tomography (PET) is a common and reliable...

Published: 4/3/2023 | Inventor(s): Lars Furenlid, Xin Li

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Sensors and Detection

Method for Diagnosing, Imaging, and Treating Overwhelmed Myelin Lipid Processing within Immune Cells in the Brain After Stroke

It was discovered that foam cells form within primary infarcts and areas of secondary neurodegeneration after stroke. This invention provides for a method of noninvasive imaging and assessment of fatty acid oxidation in the brain after stroke using radionuclide and magnetic resonance-based imaging currently used to measure myocardial fatty acid oxidation...

Published: 4/3/2023 | Inventor(s): Kristian Doyle

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Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Diagnostics

Fast Volumetric Imaging of Fluorescent Tissue Structures and Activities

Researchers at the University of Arizona have developed a novel microscope imaging technique that generates high-resolution large-volume 3D images of tissue at subcellular resolution, and captures transient activities within the volume at 100 volume frames per second (vps). The invention breaks away from the traditional plane-scanning approach and implements...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Jun Ding, Dongli XU

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Camera-Based Surgical Microscope with Display

This invention is a compact surgical microscope that provides an increased depth of focus and wide field of view from various angles of the surgical field. Information from multiple wavelengths, including visible and NIR can be overlaid on a single display monitor. The monitor is mounted so that several people can view it at the same time, with no neck...

Published: 4/3/2023 | Inventor(s): Rongguang Liang

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A Multi-Functional Three-Dimensional Microscopic System with Structured Illumination and Optical Depth Scanning

This technology is a telecentric microscope design that reconciles the resolution vs. depth of field issues associated with microscope systems. The microscope's design maintains constant system magnification while it performs a depth scan with an electrically controlled vari-focal lens. Background: The classic tradeoff between optical resolution...

Published: 4/3/2023 | Inventor(s): Hong Hua, Sheng-Huei Lu

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Method for 3D Nonlinear Structured Illumination Super-resolution Imaging

Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Yu Li, Han Zhang

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Method of Simultaneous Frequency-Sweeping Lifetime Measurements on Multiple Excitation Wavelengths

A new lifetime imaging system that can fully measure the FRET network between five fluorescent labels in a single image scan has been developed at the University of Arizona. This technology is capable of performing hyper-dimensional lifetime imaging on multiple excitation wavelengths simultaneously, allowing for previously not achievable FRET imaging...

Published: 4/3/2023 | Inventor(s): Leilei Peng, Ming Zhao

Keywords(s): fluorescence lifetime, frequency-sweeping

Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Imaging & Optics

Frequency Domain Reconstruction System for Microgrid Imaging Polarimeters

Researchers at the University of Arizona have developed the concept for a camera system that is able to perform polarimetric imaging with ease while simultaneously implementing instrumentation that reduces polarization artifacts. The system uses technology currently existing in handheld cameras to perform polarization imaging in a novel way that allows...

Published: 4/3/2023 | Inventor(s): J. Scott Tyo, Bradley Ratliff

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Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging

Parallel Multi-Point Scanning Confocal Imaging

Researchers at The University of Arizona's James C. Wyant College of Optical Sciences have designed a confocal microendoscopic multi-point scanning system. This system has approximately the same resolution of a single point scan system while maintaining the high frame rate of the slit-scan system at 30 fps. A prototype has demonstrated that for...

Published: 4/3/2023 | Inventor(s): Arthur Gmitro, Andrew Rouse, Anthony Tanbakuchi

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