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Vascular Plug
This technology is a small rubber item that is designed to fit in blood vessels to stop blood loss by plugging the vessels to allow for ligation of the vessel during surgical procedures. These plugs will come in slightly varied sizes to allow them to fit in any vessel. Background: The World Health Organization estimates that 234.2 million surgical...
Published: 5/25/2022   |   Inventor(s): Craig Weinkauf, Scott DeRigne
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Life Sciences, Technology Classifications > Materials > Medical Devices
Amphipathic Helical Glycopeptide Address Sequences for Enhanced Blood-Brain Barrier Transport of Neuroactive Peptides
University of Arizona researchers have successfully created a series of amphipathic helical glycopeptides with the ability to retain a membrane bound conformation promoting endocytosis as well as a water-soluble conformation facilitating exit from the membrane. This "biousian" property is intrinsic in allowing the molecule to traverse the...
Published: 5/6/2022   |   Inventor(s): Robin Polt, Dhanasekaran Muthu
Keywords(s):  
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Engineering & Physical Sciences
Peptide-Based Modulators of HMGBl Activity Protect Against Cell Damage and Inflammation
This technology assists with the inhibition of HMGB1 to decrease the body’s inflammatory response which occurs when the HMGB1 protein binds to DNA and TLR4. By decreasing HMGB1 binding to DNA, cell inflammation can be significantly reduced, thus preventing further cell damage. This technology can be used in a large spectrum of diseases, such as:...
Published: 5/5/2022   |   Inventor(s): Ruslan Rafikov, Olga Rafikova
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Category(s): Technology Classifications > Life Sciences, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation
Novel mRNA-based Prognostic Index Derived from Differential Expression Analysis Improves Overall Survival Estimates in Glioblastoma
This technology is a set of biomarkers to predict radiotherapy and chemotherapy outcomes in individual Glioblastoma Multiforme patients to better assess their prognosis and therapy. Background: Glioblastoma Multiforme (GBM) is the most aggressive form of brain cancer and is currently treated through surgical intervention, chemotherapy and radiotherapy....
Published: 4/19/2022   |   Inventor(s): Eric Weterings, Baldassarre Stea, Daruka Mahadevan, Michael Hammer, Christopher Morrison
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Category(s): Technology Classifications > Life Sciences, Technology Classifications > Healthcare Portfolios
Bioimpedance System for Enhanced Positional Guidance
This technology is a biopsy system utilizing bioimpedance guidance to overcome limitations of current needles used in biopsy procedures. The research also provides bioimpedance based electrical control of bleeding complications. Background: According to statistics published by the World Health Organization, cancer has become one of the leading causes...
Published: 4/19/2022   |   Inventor(s): Michael Larson, Charles Hennemeyer
Keywords(s):  
Category(s): Technology Classifications > Life Sciences
Mode Scrambler for Increasing Numerical Aperture
This project is one of the three improvements to a falloposcope under development described in UA19-249. This falloposcope was designed with optical elements selected for detection of early stage ovarian cancer in fallopian tube epithelium. The mode scrambler improvement in this project acts to widen and brighten the illumination profile to better serve...
Published: 4/14/2022   |   Inventor(s): Jennifer Barton, Kelli Kiekens, Gabriella Romano
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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Life Sciences, Technology Classifications > Materials > Medical Devices
Variance of Fixed Joint Space Width and Nomogram to Predict Knee Replacement using Measures from Fixed Flexion Knee X-rays
The cartilage underneath our knees keeps the bones in our legs from rubbing together. Unfortunately for many, this cartilage wears abnormally thin over time and causes physiological problems. If, however, this can be detected before it becomes a serious issue for the patient, then the patient can receive treatments before the painful problem can be...
Published: 3/2/2022   |   Inventor(s): Chian Kwoh, Erin Ashbeck, Edward Bedrick
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Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone, Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Simulators and Modeling Tools
Innovative Approaches to Optimize the Therapeutic Benefits of Autophagy Inhibition
This technology consists of novel, soluble compounds that are to be used to inhibit autophagy that can lead to pathogenesis of many different diseases and health conditions. Background: Autophagy is the process that regulates the degradation of overabundant malfunctioning cellular components. Autophagy is vital for maintaining cell renewal processes;...
Published: 2/22/2022   |   Inventor(s): Jennifer Carew, Steffan Nawrocki, Wei Wang
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Category(s): Technology Classifications, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Small Molecules
Myofilament Based Therapeutics for Cardiac Muscle Arrhythmias and Skeletal Muscle Tremors
This invention describes a novel therapeutic approach to treat cardiac muscle arrhythmias and skeletal muscle tremors. Background: Cardiac arrhythmias, such as those that cause atrial fibrillation or sudden cardiac death (SCD), are typically viewed as electrical/conduction abnormalities that drive uncoordinated heartbeats and their downstream health...
Published: 2/10/2022   |   Inventor(s): Samantha Harris
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences
Tunable Fluorescent Indolizine Tetracycles
This technology is tunable fluorescent probes that are able to span the colors of the rainbow. The main benefit of this technology is that it can be prepared in only one or two steps; as opposed to the five to seven steps it would normally take. Not only is this technology quicker, but the cost of goods is also more reasonable and compares very favorably...
Published: 1/18/2022   |   Inventor(s): Christopher Hulme, Nathan Bedard
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Reagents
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