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Shrimp Viral Promoters for Gene Expression and Uses Thereof
This is a novel promoter for gene expression that can be used across species. The role animal and insect research play in the development of new medical technologies for humans is quite integral. By understanding their genetic makeup, we can learn how to improve human life. Viruses that affect crustaceans may be able to provide insight into genetic...
Published: 4/3/2023
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Inventor(s): Arun Dhar, Nam Hung Mai
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications, Technology Classifications > Agriculture & Horticulture > Aquaculture
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Synapse Surgery Tools for Neural Circuit-Specific Synapse Ablation and Modification
Researchers at the University of Arizona have developed novel synapse manipulation tools, so called synapse surgery tools, using the endogenous synapse pruning system. Complement proteins tagging system for target synapses are effective in eliminating specific synapses relevant to neuronal functions and diseases. To accomplish this, the technology is...
Published: 4/24/2023
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Inventor(s): Deveroux Ferguson, Hee-Dae Kim
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Research Tools
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Organoid Models of Pituitary Adenomas
This technology is a patient-derived organoid of a pituitary adenoma for the purpose of identifying treatment for Cushing’s Disease (CD). The lack of specificity of current standard of care treatments with low efficacy and tolerability makes CD a medical therapeutic challenge. One major limitation to developing new medical therapies is the lack...
Published: 4/3/2023
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Inventor(s): Yana Zavros, Andrew Little
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Healthcare Portfolios > Diabetes, Metabolism, Endocrinology & Obesity
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A Device for Simultaneous Measurement of Pulmonary Ventilation and Metabolic Rate in Neonatal Rodents
University of Arizona researchers have developed a way of measuring and studying neonatal rodents' breathing activity and metabolic rate simultaneously using this homemade dual chamber technology. This inexpensive and simple tool is also useful for comparing the ventilatory and metabolic responses to various stressors, including hypoxia, acute inflammatory...
Published: 4/3/2023
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Inventor(s): Ralph Fregosi, Christina Hoyer-Kimura
Keywords(s):
Category(s): Technology Classifications > Research Tools
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Variance of Fixed Joint Space Width and Nomogram to Predict Knee Replacement using Measures from Fixed Flexion Knee X-rays
The cartilage underneath our knees keeps the bones in our legs from rubbing together. Unfortunately for many, this cartilage wears abnormally thin over time and causes physiological problems. If, however, this can be detected before it becomes a serious issue for the patient, then the patient can receive treatments before the painful problem can be...
Published: 4/3/2023
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Inventor(s): Chian Kwoh, Erin Ashbeck, Edward Bedrick, Jeffrey Duryea
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone, Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Simulators and Modeling Tools
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Variable-Pressure Head-Out Plethysmography Chamber with Data Acquisition and Analysis Software
Animal studies have always been a large part of scientific and medical discoveries both for the animals being studied and for eventual human application. Plethysmography, studying the changes in the volume of a body or organ, is a critical part of those studies. Here specifically is the study of respiration endpoints in mice and rats given different...
Published: 4/3/2023
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Inventor(s): Kyle Kentch, Stephanie Bruggink, Benjamin Renquist
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Software & Information Technology
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Disposable Partial Vertebrate Animal Cage Divider
This technology is a unique animal welfare product that mimics burrow-like structures, increases engagement, and reduces aggression. The innovation was designed at a University of Arizona laboratory for group-housed mice.
Background:
Current caging technologies remain expensive and inadequate to provide vertebrate lab animals with separation from...
Published: 4/3/2023
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Inventor(s): Bret Tallent, Jonathan Lifshitz
Keywords(s):
Category(s): Technology Classifications > Research Tools, Technology Classifications > Creative Works, Technology Classifications > Veterinary Medicine
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Tunable Fluorescent Indolizine Tetracycles
This technology is tunable fluorescent probes that are able to span the colors of the rainbow. The main benefit of this technology is that it can be prepared in only one or two steps; as opposed to the five to seven steps it would normally take. Not only is this technology quicker, but the cost of goods is also more reasonable and compares very favorably...
Published: 4/3/2023
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Inventor(s): Christopher Hulme, Nathan Bedard, Andrew Sennett
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Reagents
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Apparatus for Active Tissue Scaffold Stretching in Cell Culture Conditions
This invention is a means to apply controlled dynamic forces on a macroscale tissue scaffold along a period of cell culture conditions that can range from minutes to weeks. This apparatus uses a mechanically compliant substrate, which can be made from various materials, that supports the attached tissue scaffold. The apparatus also contains a holder...
Published: 4/3/2023
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Inventor(s): Ashlee Harris, Jerome Lacombe, Baiju Thomas, Matthew Barrett, Frederic Zenhausern, Alan Nordquist
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Simulators and Modeling Tools
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9A7 Monoclonal Ab
This invention is an IgG2b monoclonal antibody that targets vitamin D receptor (VDR) and is made and derived from Lewis rats with partially purified chicken intestinal vitamin D receptor.
Background:
1,25-dihydroxyvitamin D3 receptor (VDR) is implicated in a range of inflammatory, dermatological, osteoporosis, cancers and autoimmune conditions. The...
Published: 4/3/2023
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Inventor(s): Carol Haussler, Mark Haussler, J. Wesley Pike, Samuel Marion
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Research Tools
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