All-Fiber Single-Cavity Dual-Comb for Coherent Anti-Stokes Raman Scattering Spectroscopy based on Spectral Focusing

Case ID:

This technology is an all-fiber, single-cavity, free-running, dual-comb laser system based on spectral focusing. This technique can be used in coherent anti-Stokes Raman scattering spectroscopy (CARS) and label-free imaging for a variety of applications.

Coherent anti-Stokes Raman scattering spectroscopy (CARS) is a form of spectroscopy used primarily in chemistry, physics, and related fields. It employs multiple photons to address molecular vibrations and produces a coherent signal. A benefit of CARS is the it is a label-free imaging technique that can be used in species that do not fluoresce.


  • Coherent Raman Spectroscopy
  • Label-free imaging


  • Bidirectional laser
  • Spectral focusing
  • Laser shift from 1560nm to 1060nm
Patent Information:
Contact For More Information:
Richard Weite
Senior Licensing Manager, College of Optical Sciences
The University of Arizona
Lead Inventor(s):
Khanh Kieu
Yukun Qin