Invention:
Invention:
An improved process of chemical conversion of the natural plant product physachenolide D (PCD) to a C-18 analogue (LG-134) of physachenolide C (PCC).
Background:
The standard yield of LG-134 using current methods is relatively low at 1/3 resultant from original products. This method allows for the yield to be double current chemical processes. LG-134 is especially important due to its potent anticancer activity against prostate cancer and melanoma
Applications:
• Chemical yield of LG-134
Advantages:
• More efficient
• Yield from starting material is doubled compared to previous methods.
Licensing Manager:
Tod McCauley
TodM@tla.arizona.edu
520-626-7916