Compositions for Treating and Preventing Lung Disease

Case ID:

This invention is a novel pharmaceutical composition for supplemental expression of a protein for the treatment of asthma and other pulmonary diseases. This method utilizes a surfactant protein, delivered via aerosolization to offer a more effective treatment option.

Asthma medicines of the 1940’s and 1950’s consisted of epinephrine injections (adrenaline) and aminophylline tablets or suppositories. In the 1960’s oral combinations were the staples of chronic therapy. More modern methods of asthma treatment involve bronchodilators or beta agonists that work to reduce the swelling and mucus inside the airways to aid in breathing. This new method of synthesis involves the inhalation of a biologic encapsulating a necessary protein required for the control of inflammatory processes in the alveolar space.


  • Treatment for asthma
  • Treatment for other related pulmonary diseases


  • Targets cells directly 
  • Offers delivery via aerosolization for efficacious administration
  • Tailored asthma treatment
Patent Information:
Contact For More Information:
Mitch Graffeo
Sr. Licensing Manager - COM-T
The University of Arizona
Lead Inventor(s):
Julie Ledford