Molecular Imaging for High-Risk Carotid Plaques

Case ID:

This invention is a molecular probe that enables a non-invasive method for detecting vulnerable plaque in the carotid artery prior to its rupture.



Approximately 140,000 Americans die from stroke—these stroke-caused deaths occur every four minutes. Carotid atherosclerotic disease causes between 20% and 25% of all strokes. A carotid endarterectomy (CEA) is a surgical procedure to remove plaque in the carotid artery, which reduces the stroke rate. The benefits of CEA surgeries are much greater in symptomatic patients than in asymptomatic patients. There is a need for a non-invasive imaging method for determining which asymptomatic patients may benefit from CEA surgical therapy.      



  • Molecular imaging for stroke risk assessment



  • Non-invasive imaging
  • Improved selection of patients for carotid endarterectomy (CEA)
Patent Information:
Contact For More Information:
Mitch Graffeo
Sr. Licensing Manager - COM-T
The University of Arizona
Lead Inventor(s):
Craig Weinkauf
Terry Matsunaga
Jonathan Lindner
Evan Unger
Edmund Marinelli