MTS-LOF: Medical Time-Series Representation Learning via Occlusion-Invariant Features

Case ID:

Medical Time Series Representation Learning, known as MTS-LOF, uses the strengths of contrastive learning and Masked Autoencoder (MAE) methods, providing more sophisticated, context-rich representations, while also clarifying the interplay between temporal and structural dependencies in healthcare data. MTS-LOF is ideal for integration into numerous healthcare applications, ranging from sleep quality analysis and fall detection to seizure prediction. Furthermore, there is potential to refine MTS-LOF for deployment on smartphones integrated with wearable sensors, such as smartwatches and EEG headsets, facilitating real-time prediction and continuous monitoring. 

Medical time series data refers to information collected over time from patients using various sensors and devices. This data is crucial for understanding diseases, planning treatments, and managing patients' health. Traditional methods require manual labeling of medical data, which can be time-consuming and expensive. Unlike traditional approaches to analytics that simply present processed information from the past, predictive analytics uses historical and real-time data to forecast future events and identify trends in patient care. To achieve this, predictive analytics employs a variety of techniques, including data mining, statistics, artificial intelligence, and machine learning. Predictive healthcare, especially in personal use, allows for more patient autonomy and self-empowerment. 


  • Personal healthcare 
  • Neurological monitoring
  • Healthcare data analysis


  • Large range of applications
  • Builds on current technologies (smartphones, other healthcare analytics, etc.)
  • Increased efficiency of data labeling
Patent Information:
Contact For More Information:
Jay Martin
Licensing Associate, Software and Copyright
The University of Arizona
Lead Inventor(s):
Ao Li
Huayu Li
Ana Carreon-Rascon