Search Results - clara+curiel

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Pharmacological Inhibition of PD-L1 as an Antagonist of Skin Damage and Cancer in response to Acute and Chronic Solar UV Exposure and Other Environmental Toxicants
This innovation is the development of a pharmacological inhibitor of PD-L1 to prevent or reduce the negative impact of acute and chronic solar UV exposure and environmental toxicants on the skin. PD-L1 is a molecule involved in immune regulation and can be upregulated in response to UV radiation and environmental toxins. However, overexpression of PD-L1...
Published: 3/6/2024   |   Inventor(s): Sally Dickinson, Georg Wondrak, Clara Curiel
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Dermatology
Methods and System for Closed-Loop Ultrasound and Photoacoustic Imaging
This technology is a novel closed-loop volumetric ultrasound and photoacoustic imaging and spectroscopy method that is operator-independent. The technology can be integrated with existing hardware systems, and it offers the flexibility to scale from standard clinical ultrasound to high-frequency preclinical imaging for visualizing structures at different...
Published: 1/16/2024   |   Inventor(s): Russell Witte, Eric Reichel, Clara Curiel, Christopher Salinas, Delaney Stratton
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Dermatology
Methods and Apparatus for High-Resolution Tissue Microscopy
This technology is a new type of microscope that allows for rapid diagnosis of skin lesions on a person’s body without the need for invasive procedures. This technology further advances noninvasive skin microscopy techniques, providing a solution that increases diagnostic accuracy and reduces time to diagnose. It can be used on its own or in...
Published: 6/6/2024   |   Inventor(s): Dongkyun Kang, Jingwei Zhao, Clara Curiel
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging
Design and Development of Innovative Formulations of Resatorvid for Targeted Skin Drug Delivery and Applications Therein
University of Arizona researchers have developed a novel formulation of Resatorvid, a selective TLR4 inhibitor that was originally designed for the treatment of sepsis. This re-formulation is designed for delivery to the skin for a variety of skin diseases including early stages of skin cancer. Background: Skin cancers tend to be slow growing and can...
Published: 11/16/2023   |   Inventor(s): Heidi Mansour, Victor Ruiz, Sally Dickinson, Clara Curiel, Hsiao-Hui Chow, Georg Wondrak
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics
Biomarker to Assess Risk For Skin Cancer Development
This technology is a diagnostic test that can help assess a patient's risk for developing skin cancer by measuring biomarker levels under specified conditions. Additionally, the test can help determine prophylactic treatment for an individual at risk of developing skin cancer. Background: Skin cancer is the most common type of cancer among the...
Published: 11/16/2023   |   Inventor(s): Clara Curiel, Amanda Fern Baker, Sally Dickinson, Emmanuel Petricoin III
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Dermatology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics