Search Results - edita+navratilova

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Treatment of Craniofacial Pain Disorders
This invention uses the gene-editing technique CRISPR/Cas9 to target pain-related proteins in the trigeminal ganglion. This editing was shown to inhibit migraine-like pain in female mice and has potential to treat craniofacial pain disorders and has long-lasting analgesic effects. Background: Many people suffer from craniofacial pain disorders, with...
Published: 7/15/2022   |   Inventor(s): Frank Porreca, Edita Navratilova, Aubin Moutal, Rajesh Khanna
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios
Kappa Opioid Receptor Antagonists for Sleep Disorders
Researchers at UArizona have discovered that kappa opioid receptors influence sleep in mice struggling with chronic pain. In particular they found that a kappa opioid receptor antagonist could be beneficial for improvement of sleep related to pain conditions, as well as other conditions where increased kappa opioid receptor signaling has been observed....
Published: 7/15/2022   |   Inventor(s): Frank Porreca, Hisakatsu Ito, Edita Navratilova
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Life Sciences > Therapeutics