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Automated Lipid Exchange-Mass Spectrometry System
This invention is an automated label-free method to measure the affinity of membrane proteins for lipids by using conventional small molecule mass spectrometry (MS) to monitor lipid exchange between lipoprotein nanoparticles called nanodiscs. We call this method lipid exchange-mass spectrometry (LX-MS). The concept is that if a membrane protein binds...
Published: 4/3/2023   |   Inventor(s): Michael Marty, James Keener, Guozhi Zhang
Category(s): Technology Classifications > Research Tools > Protein