Search Results - jean+wilson

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A Mitochondria-Focused Mouse Model (DRP-1-/- mouse) to Accelerate Gastrointestinal Pathophysiology Research
This invention is a transgenic DRP-1-/- mouse model that will help address the central role of mitochondrial structure-function dynamics in the mammalian intestine. This mouse model harbors an intestine-specific disruption in DRP-1, a key mitochondrial membrane-associated protein, which will be useful in assessing how mitochondrial structure/interaction...
Published: 5/20/2024   |   Inventor(s): Virinchipuram Viswanathan, Gayatri Vedantam, Jean Wilson, Jennifer Lising
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Animal Models
A Mitochondria-Focused Mouse Model (OPA-1-/- mouse) to Accelerate Gastrointestinal Pathophysiology Research
The invention is two engineered OPA-1-/- mouse models that will help address the central role of mitochondrial structure-function dynamics in the mammalian intestine – a translationally critical, but extremely underdeveloped, resource. This mouse models harbor an intestine-specific disruption in OPA-1, a key mitochondrial membrane-associated protein,...
Published: 5/20/2024   |   Inventor(s): Virinchipuram Viswanathan, Gayatri Vedantam, Jean Wilson, Jennifer Lising
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Animal Models