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Small Molecules with Antifungal Activity for Cryptococcosis
Researchers at the University of Arizona have found 140 novel antifungal compounds with the potential to treat cryptococcosis. These compounds have anti-Cryptococcus neoformans activity with IC50 less than 10 uM. Background: Fungal infections, although not very contagious, have affected 300 million people worldwide. Cryptococcosis is caused by opportunistic...
Published: 1/10/2024   |   Inventor(s): Hongmin Li, Anil Tharappel, Zhong Li
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
Small Molecules with Antifungal Activity for Cryptococcosis
Researchers at the University of Arizona have found 140 novel antifungal compounds with the potential to treat cryptococcosis. These compounds have anti-Cryptococcus neoformans activity with IC50 less than 10 uM. Background: Fungal infections, although not very contagious, have affected 300 million people worldwide. Cryptococcosis is caused by opportunistic...
Published: 1/10/2024   |   Inventor(s): Hongmin Li, Anil Tharappel, Zhong Li
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
Dual-View Microscope
A new type of microscope objective that integrates simultaneous co-axis low-resolution wide field of view (FOV) imaging with high-resolution small field of view imaging. A waveguide is used to relay the pupil of the wide field of view imaging system to the axis of the objective. The system addresses limitations of state-of-the-art microscope objectives...
Published: 1/10/2024   |   Inventor(s): Rongguang Liang, Shaobai Li
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Joint Space Quantification of Multiple Carpal Bones of Wrist-based on 3D Imaging
This technology is a software that is able to calculate the distance between joints among the carpal bones using 3D imaging, such as CT scan or MRI. Traditional joint space distance is calculated in a single joint for example the knee in 2D or 3D. The wrist has 8 carpal bones and forms many joints, and it is novel to quantify the joint space among these...
Published: 11/2/2023   |   Inventor(s): Zong-Ming Li
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Sensors & Controls, Technology Classifications > Software & Information Technology
Concentrated Solar Receiver and Reaction Chambers for Hydrogen Production using Solar Energy
This technology is a solar receiver tower that has a set of reciprocally rotatable chambers that receive different amounts of solar energy at the tower. This differentiates the temperatures of each chamber to house different stages of thermochemical reactions for hydrogen production. Using solar energy to produce hydrogen for fuel is a solution for...
Published: 11/13/2023   |   Inventor(s): Peiwen Li
Keywords(s):  
Category(s): Technology Classifications > Energy, Cleantech & Environmental > Renewable Energy, Technology Classifications > Energy, Cleantech & Environmental > Renewable Energy > Solar/Photovoltaic, Technology Classifications > Energy, Cleantech & Environmental > Low Carbon
Broad Spectrum Inhibitors against Viral Methyltransferases
This innovation is a universal high throughput screening (HTS) assay to identify inhibitors targeting a binding site of viral methyltransferases (MTases) with a methyl donor. The inventors developed a fluorescence polarization (FP)-based HTS assay to target reference MTases, an essential enzyme to methylate the 5’-cap of viral RNA genome on SARS-CoV-2...
Published: 11/16/2023   |   Inventor(s): Hongmin Li, Zhong Li
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
Broad Spectrum Inhibitors against Viral Methyltransferases
This innovation is a universal high throughput screening (HTS) assay to identify inhibitors targeting a binding site of viral methyltransferases (MTases) with a methyl donor. The inventors developed a fluorescence polarization (FP)-based HTS assay to target reference MTases, an essential enzyme to methylate the 5’-cap of viral RNA genome on SARS-CoV-2...
Published: 11/16/2023   |   Inventor(s): Hongmin Li, Zhong Li
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
Virtual Reality Neuropsychological Assessment (VRNA) System
This technology is a computerized neuropsychological assessment system to rapidly measure cognitive and behavioral abilities and impairments. This system operates by extracting multiple, simultaneous performance metrics while the patient is in a virtual reality (VR) game-like scenario. As the patient is playing this challenging VR video game, the VRNA...
Published: 8/9/2023   |   Inventor(s): William Killgore, Janet Roveda, Jerzy Rozenblit, Ao Li, Huayu Li
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Physical Medicine & Rehabilitation, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Mobile Application, Technology Classifications > Software & Information Technology > Bioinformatics, Technology Classifications > Software & Information Technology
Virtual Reality Neuropsychological Assessment (VRNA) System
This technology is a computerized neuropsychological assessment system to rapidly measure cognitive and behavioral abilities and impairments. This system operates by extracting multiple, simultaneous performance metrics while the patient is in a virtual reality (VR) game-like scenario. As the patient is playing this challenging VR video game, the VRNA...
Published: 8/9/2023   |   Inventor(s): William Killgore, Janet Roveda, Jerzy Rozenblit, Ao Li, Huayu Li
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Physical Medicine & Rehabilitation, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Mobile Application, Technology Classifications > Software & Information Technology > Bioinformatics, Technology Classifications > Software & Information Technology
Optical System for Spectral Imaging
This technology is an optical system with freeform elements that disperses and images the light from an object to a digital sensor for spectral imaging. Compared to traditional systems, which use rotationally symmetric optical systems with a separate dispersion element, the current invention is much more compact and low-cost. The optical system with...
Published: 9/20/2023   |   Inventor(s): Rongguang Liang, Shaobai Li
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
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