Search Results - roberta+brinton

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Sex and APOE Genotype Precision Therapeutic Targets Discovery for Alzheimer’s disease
­Title: Nutraceutical Formula for Alzheimer's and other Neurodegenerative Diseases Invention: This technology encompasses a formulation for patient subgroup-specific supplement for the treatment and therapy of Alzheimer's and other neurodegenerative diseases. These formulations can range in delivery method (food, drink, pill) and can be...
Published: 5/5/2022   |   Inventor(s): Rui Chang, Roberta Brinton, Kuixi Zhu, Rima Kaddurah-Daouk
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Healthcare Portfolios, *Medical
Novel Knockout Model Of ER-Beta in Rat Neurons
This technology is one of a set of five rat models that is focused on the role of estrogen and its receptors within the brain. This specific rat model is an ER-beta-FloxP-Cre rat that has ER-beta knocked out specifically in neurons. Background: Progress in determining the role of estrogen and its receptors in the brain has been limited by the lack...
Published: 5/28/2019   |   Inventor(s): Roberta Brinton, Fei Yin, Tian Wang
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Life Sciences
Novel Knockout Model Of ER-Alpha in Rat Neurons
This technology is one of a set of five rat models that is focused on the role of estrogen and its receptors within the brain. This specific rat model is an ER-alpha-FloxP-Cre rat that has ER-alpha knocked out specifically in neurons. Background: Progress in determining the role of estrogen and its receptors in the brain has been limited by the lack...
Published: 5/28/2019   |   Inventor(s): Roberta Brinton, Fei Yin, Tian Wang
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Life Sciences
Novel Forebrain Neuron Specific CreERT2 Rat Model
This technology is one of a set of five rat models that is focused on the role of estrogen and its receptors. This specific rat model is forebrain neuron-specific CreERT2 rat model under the CamKII promoter. Background: Progress in determining the role of estrogen and its receptors in the brain has been limited by the lack of translatable rat models...
Published: 5/28/2019   |   Inventor(s): Roberta Brinton, Fei Yin, Tian Wang
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Life Sciences
Novel Conditional Knockout Model Of ER-Beta in Rats
This technology is one of a set of five rat models that is focused on the role of estrogen and its receptors within the brain. This specific rat model is an ER-beta FloxP rat that can be combined with tissue-specific Cre rats to generate ER-beta knockouts in any tissues expressing the estrogen receptor. Background: Progress in determining the role...
Published: 5/28/2019   |   Inventor(s): Roberta Brinton, Fei Yin, Tian Wang
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Life Sciences
Novel Conditional Knockout Model of ER-Alpha in Rats
This technology is one of a set of five rat models that is focused on the role of estrogen and its receptors within the brain. This specific rat model is an ER-alpha FloxP rat that can be combined with tissue-specific Cre rats to generate ER-alpha knockouts in any tissues expressing the estrogen receptor. Background: Progress in determining the role...
Published: 5/28/2019   |   Inventor(s): Roberta Brinton, Fei Yin, Tian Wang
Keywords(s):  
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Research Tools > Animal Models