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AtriaLink: Custom Implantable Pacing Platform with BLE Control to Induce Persistent Atrial Fibrillation in Large Animal Models
This technology, AtriaLink, is a custom implantable cardiac pacing platform developed in collaboration between the Goldman and Gutruf Laboratories at the University of Arizona. It is designed to provide a fully configurable and implantable system for induction of persistent atrial fibrillation (AFib) in swine through chronic atrial pacing. The device...
Published: 5/18/2026
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Updated: 5/18/2026
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Inventor(s): Steven Goldman, Talal Moukabary, Philipp Gutruf, Daniel Benson, Fox Bravo, Rey Mendoza, Jesse Riemenschneider, Lucas Mellinger, Kian Sadat, Adrian Grijalva
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Health Education, Medical Training and Operations, Technology Classifications > Medical Devices, Technology Classifications > Research Tools > Animal Models
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Companion Diagnostic for Immunomodulatory Repair Treatments
This technology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
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Updated: 5/30/2025
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Inventor(s): Steven Goldman, Daniel Benson, Adrian Grijalva, Jordan Fink, Jordan Lancaster, Jennifer Koevary, Simar Singh
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Healthcare Portfolios > Heart and Vascular
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Custom Coded Raspberry Pi Pico to Induce Atrial Fibrillation in Swine
This invention is a low cost, reproduceable device designed to reproduce atrial fibrillation (AFib) in swine to create a large animal model of persistent AFib. Using a Raspberry Pi Pico microcontroller to burst pace, this device allows for more modularity and can be programmed with many common programming languages. This large animal model can help...
Published: 1/21/2025
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Updated: 12/16/2024
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Inventor(s): Steven Goldman, Fox Bravo, Adrian Grijalva, Talal Moukabary, Alan Salciccioli
Keywords(s):
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Heart and Vascular
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Mechanism of Tissue Regeneration
This invention is a biodegradable patch seeded with human neonatal dermal fibroblasts and human-induced pluripotent stem cell-derived cardiomyocytes, which helps regenerate endogenous cardiomyocytes in adult murine, rat and swine models of myocardial infarction as a cause of chronic heart failure (CHF). This invention details changes in specific gene...
Published: 2/3/2025
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Updated: 5/24/2023
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Inventor(s): Steven Goldman, Jennifer Koevary, Jordan Lancaster, Jordan Fink, Adrian Grijalva
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Regenerative Medicine / Tissue Engineering, Technology Classifications > Life Sciences > Therapeutics
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