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This invention describes a set of novel molecules that target and degrade DYRK/CLK for several potential therapeutic purposes. Background: Proteolysis-targeting chimeric molecules (PROTACs) are small molecules used to decrease a gene’s protein expression by targeting the protein for ubiquitination and degradation after it is created. This mechanism...
Published: 11/16/2023   |   Inventor(s): Christopher Hulme, Kevin Schofield, Walter Becker, Garrit Wilms
Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics