A Multi-Functional Three-Dimensional Microscopic System with Structured Illumination and Optical Depth Scanning

Case ID:

This technology is a telecentric microscope design that reconciles the resolution vs. depth of field issues associated with microscope systems. The microscope's design maintains constant system magnification while it performs a depth scan with an electrically controlled vari-focal lens. 


The classic tradeoff between optical resolution and depth of field in microscopy forces a conventional system to take measurements at different depths and then reconstruct three-dimensional data for an extended depth of field (EDOF), a time-consuming process due to the limited speed of mechanical movement and complexity of data extraction.



  • High-performance freeform optics metrology
  • Biomedical imaging


  • Achieves high resolution and depth of field information
  • Supports multiple imaging modalities
  • Addresses the limitations of conventional microdeflectometry and EDOF

Status: issued U.S. patent #10,725,279

Patent Information:
Contact For More Information:
Richard Weite
Senior Licensing Manager, College of Optical Sciences
The University of Arizona
Lead Inventor(s):
Hong Hua
Sheng-Huei Lu