Photothermal Microscopy Using Whispering Gallery Microcavities

Case ID:

This invention uses a photothermal spectroscopy method to detect and identify individual molecules/particles without the use of fluorescent tags or radioactive ligands. Whispering gallery optical sensor technologies are on the cutting edge of biosensing technology. Photothermal microscopy has found applications in diverse fields, including materials science, nanotechnology, biology, and medicine, offering valuable insights into thermal transport phenomena, photothermal interactions, and thermal properties of complex structures. 

Traditional methods of optical microscopy require fluorescent tags and radioactive ligands to detect and identify the molecules or particles being studied. This invention enables the ability to capture both spatial and temporal information, making it a powerful tool for studying thermal dynamics and exploring heat-related phenomena at the micro and nanoscale.


  • Medical diagnostics
  • Nanotechnology
  • Biology 
  • Materials science


  • Label-free imaging
  • High sensitivity and specificity
  • Generative 3D imaging
Patent Information:
Contact For More Information:
Richard Weite
Senior Licensing Manager, College of Optical Sciences
The University of Arizona
Lead Inventor(s):
Tsu-Te Su
Shuang Hao