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Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action
This invention describes an inhibitor of eIF4A, which is a validated cancer drug target. The inventors describe a novel mechanism by which this inhibitor works.
Background:
Oncogenic, or cancer-causing pathways have long been challenging drug targets, especially for complex cancers. One protein complex called eIF4F is key to select oncogenic pathways...
Published: 2/14/2024
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Updated: 12/6/2021
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Inventor(s): Eli Chapman, Christopher Zerio
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Healthcare Portfolios > Oncology
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