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Heart Valve for Eccentric Orifice
This technology is a novel heart valve and deployment system that maintains eccentric geometries while optimizing valve function and hemodynamics, reducing adverse events. The asymmetrical leaflet design features two identical mirrored larger leaflets and one shorter leaflet. Traditional symmetric leaflet design features three equal leaflets that rely...
Published: 11/16/2023
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Inventor(s): Marvin Slepian, Danny Bluestein, Brandon Kovarovic, Ryan Helbock
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Therapeutic, Technology Classifications > Healthcare Portfolios > Heart and Vascular
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Polymeric Heart Valve System and Method of Manufacture
This invention is a new polymer-based heart valve designed to reduce stress on the leaflets of the valve while in use in the human body, providing for longer-term durability compared to other polymer-based valves.
Background:
According to the CDC, heart disease is the leading cause of death in the United States: about one in every four deaths is due...
Published: 11/16/2023
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Inventor(s): Marvin Slepian, Danny Bluestein, Oren Rotman, Brandon Kovarovic
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Medical Devices
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Biomarker Signatures of Platelet Activation
This invention is a mechanical biomarker signature of shear effects on cells for the purpose of detecting thrombosis early so it can be treated or intercepted prior to a thrombotic event.
Background:
Thrombosis is a pathophysiological event that can trigger conditions like stroke or heart attack. The efficacy of many antithrombotic agents is shear...
Published: 4/3/2023
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Inventor(s): Marvin Slepian, Yana Roka Moiia, Danny Bluestein, Naing Bajaj, Michael Dicaro, Louise Hecker
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Oncology
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HyperShear in a Channel: A Microfluidic Facsimile of Ventricular Assist Devices to Reduce Thrombotic Risk and Enhance Patient Safety
This technology utilizes device thrombogenicity emulation--a method which mimics the shear stresses that would be exhibited within the patient in order to assess proper anti-thrombolytic therapies. Shear stresses are observed in a microfluidic facsimile of a ventricular assist device (VAD), which can quickly be translated to assess the personal risk...
Published: 11/16/2023
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Inventor(s): Marvin Slepian, Alberto Redaelli, Danny Bluestein, Marco Rasponi
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic
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