Search Results - daruka+mahadevan

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Breast Tumor Targeted Fluorescence Guidance for Intraoperative Margin Assessment
This technology is an anti-CEACAM6 antibody tagged with fluorescent labels. The idea is that these fluorescent antibodies can be used for real-time molecular fluorescence imaging to help guide the surgical removal of a tumor. This technology is targeted toward breast cancer. Background: Over half of the 270,000 breast cancer diagnoses in the United...
Published: 6/24/2024   |   Updated: 5/7/2020   |   Inventor(s): Daruka Mahadevan, David Morse, Marie Catherine Lee, Narges Tafreshi
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Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Oncology
Small Molecular Weight Inhibitors of the DNA - KU70/80 Association to Sensitize Cells for Radiation or Chemotherapy
This invention provides methods and compositions for inhibiting cancer cell survival and/or promoting cell death following radiation or chemotherapy applied in cancer treatment. Investigators found compounds that may disrupt the Ku70/80 – DNA repair association. The Ku70/80 dimer protein is involved in the repair of radiation-induced DNA double...
Published: 7/23/2024   |   Updated: 9/11/2015   |   Inventor(s): Eric Weterings, Daruka Mahadevan, Josef Vagner
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Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology