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Small Molecular Weight Inhibitors of the DNA - KU70/80 Association to Sensitize Cells for Radiation or Chemotherapy
This invention provides methods and compositions for inhibiting cancer cell survival and/or promoting cell death following radiation or chemotherapy applied in cancer treatment. Investigators found compounds that may disrupt the Ku70/80 – DNA repair association. The Ku70/80 dimer protein is involved in the repair of radiation-induced DNA double...
Published: 7/23/2024
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Updated: 9/11/2015
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Inventor(s): Eric Weterings, Daruka Mahadevan, Josef Vagner
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology
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