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The compounds discovered in this patented technology could be used as a breast cancer therapeutic drug. There are a few call signaling pathways that are heavily involved in the pathogenesis of cancer. Two of these pathways are the RAS pathway and the PI3K pathway, and both of these pathways are deregulated in the formation of human cancer. This...

Published: 4/3/2023 | Inventor(s): Emmanuelle Meuillet, Lu Chen, Shuxing Zhang

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Category(s): Technology Classifications > Life Sciences > Small Molecules

Targeting the PH/DH Domain of Tiam1 for the Treatment and/or Prevention of Bone Metastases

Tiam1 is a highly conserved exchange factor that is over-expressed in many cancers, including prostate cancer (CRPCA). Increase in Tiam1 expression is associated with increased metastases and correlates with poor PCA patient survival prognosis. This patented technology has identified a novel compound which exhibits the ability to reduce prostate cancer...

Published: 4/3/2023 | Inventor(s): Emmanuelle Meuillet, Sylvestor Moses, Shuxing Zhang

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Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Small Molecules