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Cancer treatment through hTERT inhibition

Title: Cancer Treatment Through hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...

Published: 1/7/2025 | Inventor(s): Laurence Hurley, Vijay Gokhale, HyunJin Kang, Kui Wu

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Category(s): Technology Classifications > Healthcare Portfolios > Oncology

G-Quadruplex Targeting Small Molecules for the Treatment of Castration Resistant Prostate Cancer and HSV-1

This technology consists of a new class of small-molecules that target G-quadruplex formation. These compounds have the potential to treat a wide variety of diseases including prostate cancer. In particular, these compounds are aimed at helping individuals who have developed a resistance to androgen-deprivation therapies (ADT). While most ADT therapeutics...

Published: 11/16/2023 | Inventor(s): Elsa Reyes Reyes, Cynthia Miranti, Laurence Hurley, Vijay Gokhale, Kui Wu, Sara Richter

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics