Search Results - technology+classifications+%3e+life+sciences+%3e+biologics

22 Results Sort By:
Myofilament Based Therapeutics for Cardiac Muscle Arrhythmias and Skeletal Muscle Tremors
This invention describes a novel therapeutic approach to treat cardiac muscle arrhythmias and skeletal muscle tremors. Background: Cardiac arrhythmias, such as those that cause atrial fibrillation or sudden cardiac death (SCD), are typically viewed as electrical/conduction abnormalities that drive uncoordinated heartbeats and their downstream health...
Published: 2/10/2022   |   Inventor(s): Samantha Harris
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences
Materials Selection Criteria for Electrochemical Sensing Using Organic Electrochemical Transistor (OECT)
This technology is a new method for selecting materials when designing organic electrochemical transistors (OECTs). This method aides the design of OECT-based sensors, enabling optimization for operating power level and sensitivity. Background: OECTs are transistors useful in sensing and bioelectronics because they are simple, easy to manufacture,...
Published: 2/4/2021   |   Inventor(s): Erin Ratcliff, Songyan Yu
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Materials > Medical Devices > Diagnostic
Design Guideline of Floating Gate Electrolyte-Gated Transistor (FGEGT) Sensors
This technology is a method for designing floating gate electrolyte-gated transistor-based sensors, so that the sensor achieves a maximum sensitivity while maintaining a low operating voltage. Background: Electrolyte-gated transistors (EGTs) are a type of transistor particularly useful in biosensors due to their simplicity, sensitivity, low voltage...
Published: 2/4/2021   |   Inventor(s): Erin Ratcliff, Songyan Yu
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Biologics
Amuvatinib-Dependent Degradation of Rad51 is Proteasome-Mediated
This technology is a combination of cisplatin with amuvatinib (MP-470) for the treatment of cisplatin-resistant pancreatic cancer cells. Cisplatin is a chemotherapy medication used to treat several cancers and amuvatinib is an oral drug that has been used in trials for treating solid tumors and small cell lung carcinoma. The invention is directed to...
Published: 10/6/2020   |   Inventor(s): Daruka Mahadevan, Nathan Ellis
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics
Enhanced Melanoma Cancer Prevention by Novel Melanotropins
This invention describes a method to stimulate natural production of melanin in the body. This stimulation is provided by a selective gamma-melanocyte stimulating hormone derivative, which incites the increase in melanin in the body. A natural increase confers photo protective properties without the need for UV activation, making it a safe compound. Background: Existing...
Published: 9/30/2020   |   Inventor(s): Minying Cai, Victor Hruby
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics
Topical Delivery of Natural Tanning Active Ingredient for Melanoma Prevention Using Peptides Selective for Melanocortin Receptor 1
This invention is the topical delivery of a natural peptide ingredient to aid in the production of melanin without exposure to UV radiation. The product is stable and selective for the human melanocortin-1 receptor (hMC1R), avoiding off-target effects with non-selective melanocortin ligands. Background: Melanoma is the most dangerous form of skin...
Published: 9/21/2020   |   Inventor(s): Minying Cai, Victor Hruby
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Dermatology
A Peptide Approach to Block eNOS Phosphorylation at T495
This invention is a peptide that blocks eNOS phosphorylation. These peptides are designed to target to block T495 phosporylation site of eNOS. When done, this would prevent the activation of eNOS that leads to superoxide production and overwhelming inflammation. The initial peptide has been shown to reduce NOS derived superoxide and cell barrier loss...
Published: 8/14/2020   |   Inventor(s): Stephen Black, Evgeny Zemskov, Qing Lu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Life Sciences > Biologics
Novel Amphipathic Ligands for the Dynorphin Binding Site on the Bradykinin Receptor
The core portion of the dynorphin protein was identified and modifications were made to that core to allow dynorphin to interact and antagonize a bradykinin receptor which is partially responsible for pain sensations. Applications: Since the invention antagonizes a receptor partly responsible for pain, the modified protein can be used as a form...
Published: 7/18/2020   |   Inventor(s): Yeon Sun Lee
Keywords(s): ongoing pain
Category(s): Technology Classifications > Life Sciences > Biologics
Artificial Membranes Incorporating GPCRs for Label-Free, Electrophysiological Measurements of Ligand-GPCR Interactions
This invention consists of an artificial lipid membrane that incorporates G-protein coupled receptors into its structure. It allows direct, label-free measurement of ligand binding and activation of G-protein coupled receptors. Background: G-protein coupled receptors are a superfamily of proteins that are very popular drug targets. In 2017, 34%...
Published: 7/3/2019   |   Inventor(s): Steven Scott Saavedra, Craig Aspinwall
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Materials > Biomaterials, Technology Classifications > Research Tools > Screening assays
Modification of Valve Replacements to Reduce Calcification
This invention is a modification of a replacement heart valve used for treating heart valve disease. The valve is modified with enzymes that generate adenosine, a known regulator of calcification. These tissue based heart valves will allow for the localized reduction of calcification, which will lead to a longer life span of the heart valve. Background:...
Published: 10/24/2018   |   Inventor(s): Zain Khalpey, Raymond Runyan
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biologics
1 2 3