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Non-Imaging, Random-Sampling Second Harmonic Generation Measurements to Distinguish Colon Cancer
Second-harmonic generation (SHG) microscopy has emerged as a powerful modality for imaging fibrillar collagen in a diverse range of tissues. A preliminary study demonstrated that non-imaging, randomly sampled SHG intensity measurements are likely sufficient to distinguish normal colorectal tissue from tumor/tumor-adjacent tissue with digital simulation...
Published: 9/7/2022   |   Inventor(s): Jenna Montague, Jennifer Barton, Hasina Shir
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Oncology
Diagnostic for Screening and/or Predicting Women "at risk" for the Development and Progression Endometrial Cancer
This invention describes a novel method to use metabolic markers in samples obtained from cervicovaginal lavage (CVL) and machine-learning algorithms to detect patients “at risk” for endometrial cancer (EMC). Background: Endometrial cancer (EMC) is the most common gynecological cancer. The American Cancer Society estimates that in 2021...
Published: 9/7/2022   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
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Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Women's Health
Sensitive, Low-Cost Detection of SARS-CoV-2 from Clinical Saline Gargle Samples Using Smartphone Fluorescence Microscope
This invention is a method of rapidly detecting SARS-CoV-2 in clinical saline samples using a smartphone fluorescence microscope-based immunofluorescence. This method can detect samples of SARS-CoV-2 in saline gargle solutions down to 10 ag/μl (below single copy level). A saline sample is collected, loaded onto a paper-based microfluidic chip, and...
Published: 6/24/2022   |   Inventor(s): Jeong-Yeol Yoon
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics
An Alternative Mode of RNA Interference Triggered through Feeding Synthetic RNAs that are Processed into piRNAs
This invention describes a new method of the widely-used RNA interference technique with potential clinical and research applications. Background: RNA interference is a commonly used method to knockdown or “silence” genes. This is typically done using small interfering RNA (siRNA) probes designed with specificity to bind and tag certain...
Published: 5/20/2022   |   Inventor(s): Judith Brown, Mosharrof Hossain Mondal, Jorge Rafael Paredes Montero, Alex Flynt
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Category(s): Technology Classifications > Agriculture & Horticulture, Technology Classifications > Agriculture & Horticulture > Crop Improvement, Technology Classifications > Life Sciences > RNAi/siRNA, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Therapeutics
Direct Capture and Smartphone Quantification of Airborne SARS-CoV-2 on a Paper Microfluidic Chip
This is a rapid, handheld smartphone-based paper microfluidic assay that is capable of directly detecting SARS-CoV-2 in small droplets from the air, without the need for an air sampler or a long collection time. The infected droplets are collected on a paper microfluidic chip, which then has antibody-conjugated submicron fluorescent particle suspension...
Published: 1/19/2022   |   Inventor(s): Jeong-Yeol Yoon
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
Apparatus for Reconfiguration of Components in a Micro-Physiological System
The invention is a novel apparatus utilizing modular assembly for the development of co-culture, monitoring, and study of functional interactions between different types of biological material under various environmental conditions. The buckle clamp stage-like apparatus mimics a microfluidic based system. Background: 3D in vitro models are important...
Published: 1/18/2022   |   Inventor(s): Matthew Barrett, Frederic Zenhausern, Marc Mac Giolla Eain, Paul Wilmes
Keywords(s):  
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics
Personalized Medicine Software for Generating and Analyzing Genomic Sequence
UA21-131 and UA21-132 Two Patents Pending for SYSTEMS AND METHODS FOR GENERATING AND ANALYZING A CUSTOMIZED GENOMIC SEQUENCE FOR THERAPEUTIC APPLICATIONS Software: Proof of concept software funded by Tech Launch Arizona developed by a software company is fully functional and creates consistent accurate results. MAXX Py The MAXX.py script generates...
Published: 11/2/2021   |   Inventor(s): Adam Grant
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
Decision Support Logic for Pharmacogenomics
This is a database of publicly available guidelines used in conjunction with medication recommendation algorithms. The technology is a clinical intervention support tool based upon Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines. Background: Pharmacogenomics is improving the way that patients can be treated by implementing the...
Published: 11/2/2021   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Software & Information Technology > Databases
Analytic System for Automated Prognostic Determination of Disease Risk from High-Resolution, Non-Invasive, Contrast-Free Retinal Images
This invention describes a platform by which age-related macular degeneration (AMD) prognostic determinations can be made through high-resolution, non-invasive, contrast-free retinal images and diagnostic software. Background: Currently, the leading method of diagnosis or prognosis determination for not only age-related macular degeneration (AMD),...
Published: 7/8/2021   |   Inventor(s): Mohammad Majdi, John SanGiovanni, Robert Snyder, Nirav Merchant, Emre Toker
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Diagnostics
Blood Biomarker for the Diagnosis and Treatment of Chronic Inflammation in the Brain in the Days and Weeks after Stroke
This invention comprises a method of identifying chronic inflammation in the day(s), weeks, or months after a stroke by measuring matrix metalloproteinase-12 (MMP-12) in a patient to determine whether therapeutic intervention is required to help immune cells process lipid debris after stroke to reduce secondary neurodegeneration. MMP-12 is a protein...
Published: 6/16/2021   |   Inventor(s): Kristian Doyle
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Protein
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