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Neonatal Anorectal Tonometer with Disposable/Detachable Tip
This technology is a neonatal anorectal tonometer that involves a detachable, fluid-filled tip with a quick release system involving (magnet & plate) that connects the tip to a force sensor inside the handle of the device. This device can be used as a substitute for digital rectal exams. Background: Cauda Equina Syndrome (CES) occurs when the Cauda...
Published: 1/26/2023   |   Inventor(s): Eniko Enikov
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Emergency Medicine, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Sensors & Controls, Technology Classifications > Sensors & Controls > Motion & Force
Stroke Outcome Prediction using Vascular Imaging Features
This is a prediction method to determine the outcome of a stroke based on vascular images presented by the patient. This model predicts the 90-day functional outcome after ischemic stroke at a significantly higher accuracy than current models, to inform treatment decisions and patient selection. Machine learning models were employed and trained with...
Published: 12/8/2022   |   Inventor(s): Kaveh Laksari, Aditi Deshpande, Jordan Elliott, Pouya Tahsili-Fahadan
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Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Diagnostics
Method for Diagnosing, Imaging, and Treating Overwhelmed Myelin Lipid Processing within Immune Cells in the Brain After Stroke
It was discovered that foam cells form within primary infarcts and areas of secondary neurodegeneration after stroke. This invention provides for a method of noninvasive imaging and assessment of fatty acid oxidation in the brain after stroke using radionuclide and magnetic resonance-based imaging currently used to measure myocardial fatty acid oxidation...
Published: 11/8/2022   |   Inventor(s): Kristian Doyle
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Diagnostics
Non-Imaging, Random-Sampling Second Harmonic Generation Measurements to Distinguish Colon Cancer
Second-harmonic generation (SHG) microscopy has emerged as a powerful modality for imaging fibrillar collagen in a diverse range of tissues. A preliminary study demonstrated that non-imaging, randomly sampled SHG intensity measurements are likely sufficient to distinguish normal colorectal tissue from tumor/tumor-adjacent tissue with digital simulation...
Published: 12/1/2022   |   Inventor(s): Jenna Montague, Jennifer Barton, Hasina Shir
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Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Oncology
Diagnostic for Screening and/or Predicting Women "at risk" for the Development and Progression Endometrial Cancer
This invention describes a novel method to use metabolic markers in samples obtained from cervicovaginal lavage (CVL) and machine-learning algorithms to detect patients “at risk” for endometrial cancer (EMC). Background: Endometrial cancer (EMC) is the most common gynecological cancer. The American Cancer Society estimates that in 2021...
Published: 9/7/2022   |   Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski
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Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Women's Health
Sensitive, Low-Cost Detection of SARS-CoV-2 from Clinical Saline Gargle Samples Using Smartphone Fluorescence Microscope
This invention is a method of rapidly detecting SARS-CoV-2 in clinical saline samples using a smartphone fluorescence microscope-based immunofluorescence. This method can detect samples of SARS-CoV-2 in saline gargle solutions down to 10 ag/μl (below single copy level). A saline sample is collected, loaded onto a paper-based microfluidic chip, and...
Published: 7/18/2022   |   Inventor(s): Jeong-Yeol Yoon
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Category(s): Technology Classifications > Life Sciences > Diagnostics
An Alternative Mode of RNA Interference Triggered through Feeding Synthetic RNAs that are Processed into piRNAs
This invention describes a new method of the widely-used RNA interference technique with potential clinical and research applications. Background: RNA interference is a commonly used method to knockdown or “silence” genes. This is typically done using small interfering RNA (siRNA) probes designed with specificity to bind and tag certain...
Published: 10/25/2022   |   Inventor(s): Judith Brown, Mosharrof Hossain Mondal, Jorge Rafael Paredes Montero, Alex Flynt
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Category(s): Technology Classifications > Agriculture & Horticulture, Technology Classifications > Agriculture & Horticulture > Crop Improvement, Technology Classifications > Life Sciences > RNAi/siRNA, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Therapeutics
Direct Capture and Smartphone Quantification of Airborne SARS-CoV-2 on a Paper Microfluidic Chip
This is a rapid, handheld smartphone-based paper microfluidic assay that is capable of directly detecting SARS-CoV-2 in small droplets from the air, without the need for an air sampler or a long collection time. The infected droplets are collected on a paper microfluidic chip, which then has antibody-conjugated submicron fluorescent particle suspension...
Published: 8/18/2022   |   Inventor(s): Jeong-Yeol Yoon
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Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
Apparatus for Reconfiguration of Components in a Micro-Physiological System
The invention is a novel apparatus utilizing modular assembly for the development of co-culture, monitoring, and study of functional interactions between different types of biological material under various environmental conditions. The buckle clamp stage-like apparatus mimics a microfluidic based system. Background: 3D in vitro models are important...
Published: 8/18/2022   |   Inventor(s): Matthew Barrett, Frederic Zenhausern, Marc Mac Giolla Eain, Paul Wilmes
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Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics
Personalized Medicine Software for Generating and Analyzing Genomic Sequence
UA21-131 and UA21-132 Two Patents Pending for SYSTEMS AND METHODS FOR GENERATING AND ANALYZING A CUSTOMIZED GENOMIC SEQUENCE FOR THERAPEUTIC APPLICATIONS Software: Proof of concept software funded by Tech Launch Arizona developed by a software company is fully functional and creates consistent accurate results. MAXX Py The MAXX.py script generates...
Published: 1/24/2023   |   Inventor(s): Adam Grant
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Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics
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