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Iron-targeting to stop cancer growth in malignant cells
This invention comprises a class of tetrazolium-based prochelators for targeting and binding intracellular iron for selective cancer cell antiproliferation or other iron dysregulation. Various analogues within this class of chemistry can be tuned to the redox potential for selective targeting of cancer cell types. Following cellular uptake, the tetrazolium...
Published: 3/12/2024   |   Inventor(s): Elisa Tomat, Zoufeng Xu
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences