Search Results - bereketab+mehari

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Enzymatically Released Aryl Diazonium Ions
This invention is the discovery of triazebutadienes that rapidly release aryl diazonium ions at neutral pH with a half-life of approximately one minute. Background: In 2015, the global protein therapeutics market grew to nearly $174.7 billion due to trends in targeted therapies that resulted in fewer side effects. Monoclonal antibodies and biologics...
Published: 6/20/2024   |   Inventor(s): John Jewett, Lindsay Guzman, Bereketab Mehari, Jie He
Category(s): Technology Classifications > Life Sciences
Fluorogenic Diazonium-Derived Fluorophores
This technology describes various diazonium salts that can react to produce a fluorescent azobenzene compound. Background: Current iterations of fluorescent diazonium salts utilize metal catalysts to produce a reaction. However, these metal catalysts can have harmful effects in a medical setting. This invention consists of a bioorthogonal approach...
Published: 3/12/2024   |   Inventor(s): John Jewett, Bereketab Mehari, Mehrdad Shadmehr
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Materials > Biocompatible, Technology Classifications > Materials > Biomaterials, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Medical Devices > Diagnostic