Search Results - mehrdad+shadmehr

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Quantitative Detection of Protein Misfolding or Aggregation by Chemical Labeling
This invention describes methods and systems for detecting, comparing, or evaluating proteins in a folded conformation, a particular bound state, or an aggregate state, and methods and systems for comparing amounts of labeling of a protein in a natural or control conformation and a denatured conformation. The methods of this invention may be used for...
Published: 5/31/2017   |   Inventor(s): Jacob Schwartz, John Jewett, Mahta Moinpour, Mehrdad Shadmehr
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Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Materials > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Neurology
Fluorogenic Diazonium-Derived Fluorophores
This technology describes various diazonium salts that can react to produce a fluorescent azobenzene compound. Background: Current iterations of fluorescent diazonium salts utilize metal catalysts to produce a reaction. However, these metal catalysts can have harmful effects in a medical setting. This invention consists of a bioorthogonal approach...
Published: 10/30/2015   |   Inventor(s): John Jewett, Bereketab Mehari, Mehrdad Shadmehr
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Category(s): Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Materials > Biocompatible, Technology Classifications > Materials > Biomaterials, Technology Classifications > Materials > Medical Devices > Diagnostic, Technology Classifications > Research Tools > Screening assays