Fluorogenic Diazonium-Derived Fluorophores

Case ID:
UA16-038
Invention:

This technology describes various diazonium salts that can react to produce a fluorescent azobenzene compound.

Background:
Current iterations of fluorescent diazonium salts utilize metal catalysts to produce a reaction. However, these metal catalysts can have harmful effects in a medical setting. This invention consists of a bioorthogonal approach performed under physiological conditions to produce fluorescent compounds that can be bound to specifically targeted proteins.  

Applications:

  • Biosensors
  • Detection and diagnostics
  • Medical imaging


Advantages:

  • Ideal for medical settings
  • Reduces the likelihood of false positives
  • Able to bind to various proteins
  • Targets and detects a wide variety of compounds  
Patent Information:
Contact For More Information:
Laura Silva
Sr. Licensing Manager, COS
The University of Arizona
lauras@tla.arizona.edu
Lead Inventor(s):
John Jewett
Bereketab Mehari
Mehrdad Shadmehr
Keywords: